Enhancing oxidative stability of walnuts by using gallic acid loaded lentil flour based electrospun nanofibers as active packaging material

Encapsulation of Bioactive Compounds from Aloe Vera Agrowastes in Electrospun Poly (Ethylene Oxide) Nanofibers

“…Similarly, Vatankhah [53] observed higher AO activity of cellulose acetate fibres when higher rosmarinic acid content was encapsulated. Furthermore, many authors demonstrated the antioxidant activity of polymer fibres or films incorporating natural extracts intended for food packaging applications [54,71,[114][115][116] and similar antioxidant values were obtained by using different natural extracts. Estevez-Areco et al [52] revealed an AO activity of 0.120 µmol Trolox mg −1 for electrospun PVA fibres loaded with rosemary extract, Araújo et al [117] On the other hand, it has been reported that encapsulation techniques could enhance the AO activity of natural compounds such as carotenoids [111] and curcumin [112], compared to their non-encapsulated forms.…”

“…), according to the limitations of the packaging material, are key aspects to be considered. Aydogdu et al [71] enhanced the oxidative stability of walnuts by using gallic acid loaded into lentil flour/PEO nanofibers as active packaging materials. In other studies, antibacterial nisin-loaded nanoparticles embedded within PEO nanofibers as cheese packaging to improve the anti-Listeria monocytogenes activity [72] and plasma treated PEO electrospun mats containing tea tree essential oil/β-cyclodextrin inclusion complex to extend the beef shelf life [73] were developed.…”

Evaluating the structural properties of bioactive‐loaded nanocarriers with modern analytical tools

“…It was pointed out that either alkali or acidic prepared nanofibers demonstrated depressed thermal stability in the presence of the bioactive, which was ascribed to the reduction of intermolecular forces between proteins following the encapsulation of gallic acid. From the DSC thermal scans (Figure 4e), there was no enthalpic peaks relevant to the bioactive molecule, which was an indication of losing its F I G U R E 4 Thermal properties of some bioactive-loaded nanocarriers analyzed by DSC/TGA: (a) TGA spectra of 4-Aminopyridine (4AP) and pristine halloysite; (b) 4AP-loaded halloysite nanotubes (referred to as HNT-4AP); (c) a comparison among HNT-4AP, pristine chitosan, and therapeutic-loaded polymer-nanotube composites (referred to as Cht/HNT-4AP) (Reprinted with permission from Manoukian et al, 2019); (d) gallic acid (GA) and electrospun nanofibers: (a) GA, (b) GA-loaded nanofibers at pH 10, (c) GA-loaded nanofibers at pH 1, (d) pure nanofibers at pH 1, and (e) pure nanofibers at pH 10; and (e) DSC curves of GA and electrospun nanofibers: (a) GA, (b) pure nanofibers at pH 10, (c) GA-loaded nanofibers at pH 1, (d) GA-loaded nanofibers at pH 10, and (e) pure nanofibers at pH 1 (reprinted with permission from Aydogdu et al, 2019) original crystal configuration, as an evidence of the interaction between formulation ingredients, amorphization, and successful encapsulation of gallic acid.…”

“…Thermal properties of some bioactive‐loaded nanocarriers analyzed by DSC/TGA: (a) TGA spectra of 4‐Aminopyridine (4AP) and pristine halloysite; (b) 4AP‐loaded halloysite nanotubes (referred to as HNT‐4AP); (c) a comparison among HNT‐4AP, pristine chitosan, and therapeutic‐loaded polymer–nanotube composites (referred to as Cht/HNT‐4AP) (Reprinted with permission from Manoukian et al., 2019); (d) gallic acid (GA) and electrospun nanofibers: ( a ) GA, ( b ) GA‐loaded nanofibers at pH 10, ( c ) GA‐loaded nanofibers at pH 1, ( d ) pure nanofibers at pH 1, and ( e ) pure nanofibers at pH 10; and (e) DSC curves of GA and electrospun nanofibers: ( a ) GA, ( b ) pure nanofibers at pH 10, ( c ) GA‐loaded nanofibers at pH 1, ( d ) GA‐loaded nanofibers at pH 10, and ( e ) pure nanofibers at pH 1 (reprinted with permission from Aydogdu et al., 2019)…”

“…Utilizing the beneficial attributes of nano‐driven strategies in the food/pharmaceutical fields has induced the generation of unique bioactive formulations for a broad range of applications, for example, wound dressing (Wutticharoenmongkol, Hannirojram, & Nuthong, 2019), food packaging (Aydogdu et al., 2019), and delivery purposes (Farokhzad & Langer, 2009; Ghandehari & Oupicky, 2008; Hoseyni et al., 2020). The emergence of nanodelivery systems (e.g., nanospheres, nanocapsules, nanofibers, nanocochleates, nanoballs, nanotubes, or other forms) has paved the way for efficacious diagnosis and therapy of diverse diseases (Allen & Cullis, 2013; Angelova, Drechsler, Garamus, & Angelov, 2018, 2019; Jafari & McClements, 2017; Kakkar, Traverso, Farokhzad, Weissleder, & Langer, 2017; Xu, Zeng, Lu, & Yu, 2006).…”