2024
DOI: 10.1002/smll.202400954
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Enhancing X‐Ray Sensitization with Multifunctional Nanoparticles

Jiayi Liu,
JunYong Wu,
Taili Chen
et al.

Abstract: In the progression of X‐ray‐based radiotherapy for the treatment of cancer, the incorporation of nanoparticles (NPs) has a transformative impact. This study investigates the potential of NPs, particularly those comprised of high atomic number elements, as radiosensitizers. This aims to optimize localized radiation doses within tumors, thereby maximizing therapeutic efficacy while preserving surrounding tissues. The multifaceted applications of NPs in radiotherapy encompass collaborative interactions with chemo… Show more

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Cited by 2 publications
(1 citation statement)
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“…These approaches all have the potential to be further optimized with nanoparticle-based treatments, highlighting the advancement of radiosensitizer nanoparticles. However, despite progress, challenges remain in the translation of nanoparticle-enhanced RT from the laboratory to clinical practice, including concerns about biosafety, nanoparticle clearance and the optimization of nanoparticle properties for effective interaction with radiation and biological systems ( 64 ).…”
Section: Discussionmentioning
confidence: 99%
“…These approaches all have the potential to be further optimized with nanoparticle-based treatments, highlighting the advancement of radiosensitizer nanoparticles. However, despite progress, challenges remain in the translation of nanoparticle-enhanced RT from the laboratory to clinical practice, including concerns about biosafety, nanoparticle clearance and the optimization of nanoparticle properties for effective interaction with radiation and biological systems ( 64 ).…”
Section: Discussionmentioning
confidence: 99%