Enlargement Of the Optic Disk in Childhood Optic Nerve Tumors

Systemic Abnormalities in Children with Congenital Optic Disc Excavations

“…In children, it has been reported that orbital optic glioma can cause progressive enlargement of a previously normal-sized optic disc. 20 Intracranial causes of compressive optic neuropathy include infectious disorders, aneurysms, and tumors such as gliomas, meningiomas, craniopharyngiomas, or pituitary adenomas. Approximately half of all patients diagnosed with optic pathway gliomas have neurofibromatosis.…”

Congenital Optic Nerve Anomalies

“…Optic gliomas may also cause progressive enlargement of previously normal-sized discs and should thus be evaluated with neuroimaging. 233…”

Congenital Disc Anomalies

“…The differential diagnosis of megalopapilla includes glaucoma, optic disc coloboma, and orbital optic glioma. 22 Megalopapilla may rarely be seen with other congenital abnormalities, such as basal encephalocele and midline facial anomalies. 23…”