Enterocolitis cystica profunda lesions in a patient with unclassified ulcerative enterocolitis

Abstract

Enteritis cystica profunda and diffuse colitis cystica profunda are exceedingly rare conditions. We report here the first case in which these two entities are associated in one patient. This 48-year-old woman presented initially with a solitary ulcer of the rectum and developed later deep ileal and colonic ulcerations with intervening normal mucosa, polypoid masses, and a dense fibrosis of the bowel wall. Colon and ileum specimens demonstrated submucosal mucous cysts and occasionally herniation of mucosal epithelium into the submucosa, which led to the diagnosis of enteritis and colitis cystica profunda. The exact nature of the underlying ileocolonic disease, which necessitated colectomy and extensive ileal resection, remained undetermined although an aggravating role of iterative surgical procedures is possible. Enteritis cystica profunda and diffuse colitis cystica profunda therefore seem to share a common pathogeny and have to be considered as lesions complicating an underlying disease rather than specific and autonomic diseases.

Massive gastrointestinal haemorrhage due to gastritis cystica profunda

“…The characteristic feature is the presence of wide cystic glands of pyloric type, together with epithelial lining in the cysts identical to that of crypts. The muscularis mucosae is thickened and further penetration of cystic glands into sub mucosal layer gives them the name gastritis cystica profunda [ 6 ], and not dissimilar to colitis cystica profunda where in dilated cystic glands are noted in the bowel wall and this condition has a strong association with inflammatory bowel disease [ 7 ].…”

Colitis quística profunda recidivante

“…Una de las teorías sobre la fisiopatología de la CQP es que sea secundaria a procesos de cicatrización de la mucosa y se ha asociado principalmente a la enfermedad inflamatoria intestinal y a la úlcera rectal solitaria (2,3). La principal dificultad que encontramos ante estos pacientes es el distinguir la CQP de otros procesos que pueden requerir cirugía como los tumores malignos.…”

Colitis quística profunda posradioterapia: Caso clínico

“…Si un prolapso rectal es la condición predisponente, debe ser corregido durante la cirugía para evitar recurrencias 33,34 . El pronóstico es excelente, existiendo un único reporte, donde su recurrencia terminó en pancolectomía 28 .…”