Entomological survey and report of a knockdown resistance mutation in the malaria vector Anopheles gambiae from the Republic of Guinea

Coriat, Pierre; Toto, Jean-Claude; Guibert, Philippe; Keïta, Moussa; Manguin, Sylvie

doi:10.1016/j.trstmh.2010.02.002

Cited by 14 publications

(16 citation statements)

References 23 publications

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“…The overall CSP positive rate for A. gambiae was 12.6% and 11.1% for A. melas . Previously published CSP positive rates for A. gambiae s.s. (= A. gambiae and A. coluzzii ) range between 2.24% in Guinea ( Carnevale et al , 2010) to 9.6% in Guinea-Bissau ( Jaenson et al , 1994). Earlier studies when individual species within the A. gambiae complex were not identified, infection rate of A. gambiae s.l.…”

Section: Resultsmentioning

confidence: 99%

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Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa

et al. 2014

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Presence of Plasmodium falciparum circumsporozoite protein (CSP) was detected by enzyme linked immunosorbent assay (ELISA) in a sample of Anopheles gambiae s.s., A. melas and A. pharoensis collected in Guinea-Bissau during October and November 2009. The percentage of P. falciparum infected samples (10.2% overall) was comparable to earlier studies from other sites in Guinea-Bissau (9.6-12.4%). The majority of the specimens collected were identified as A. gambiae which had an individual infection rate of 12.6 % across collection sites. A small number of specimens of A. coluzzii, A. coluzzii x A. gambiae hybrids, A. melas and A. pharoensis were collected and had infection rates of 4.3%, 4.1%, 11.1% and 33.3% respectively. Despite being present in low numbers in indoor collections, the exophilic feeding behaviors of A. melas (N=18) and A. pharoensis (N=6) and high infection rates observed in this survey suggest falciparum-malaria transmission potential outside of the protection of bed nets.

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Section: Resultsmentioning

confidence: 99%

“…Variability is also high among the Anopheles spp. implicated as vectors in this region of West Africa in terms of both their temporal population dynamics as well as species composition among study sites ( Carnevale et al , 2010; Fontenille et al , 1997a; Jaenson et al , 1994; Snounou et al , 1993). …”

Section: Introductionmentioning

confidence: 99%

Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa

et al. 2014

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“…Multi-national corporations operating in Africa recognize the burden malaria places on their staff and its impact on their commercial operations [2,3]. There is an increasing move by these multi-nationals to control malaria within the boundaries of their activities, and in many cases, extending this control to the surrounding communities [4,5]. …”

Section: Introductionmentioning

confidence: 99%

Insecticide resistance in malaria vector mosquitoes at four localities in Ghana, West Africa

Hunt

Fuseini²,

Knowles³

et al. 2011

Parasites Vectors

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BackgroundMalaria vector control programmes that rely on insecticide-based interventions such as indoor house spraying with residual insecticides or insecticide treated bed nets, need to base their decision-making process on sound baseline data. More and more commercial entities in Africa, such as mining companies, are realising the value to staff productivity of controlling malaria transmission in their areas of operation.This paper presents baseline entomological data obtained during surveys conducted for four mining operations in Ghana, West Africa.ResultsThe vast majority of the samples were identified as Anopheles gambiae S form with only a few M form specimens being identified from Tarkwa. Plasmodium falciparum infection rates ranged from 4.5 to 8.6% in An. gambiae and 1.81 to 8.06% in An. funestus. High survival rates on standard WHO bioassay tests were recorded for all insecticide classes except the organophosphates that showed reasonable mortality at all locations (i.e. > 90%). The West African kdr mutation was detected and showed high frequencies in all populations.ConclusionsThe data highlight the complexity of the situation prevailing in southern Ghana and the challenges facing the malaria vector control programmes in this region. Vector control programmes in Ghana need to carefully consider the resistance profiles of the local mosquito populations in order to base their resistance management strategies on sound scientific data.

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“…The reduced susceptibility statuses of malaria and filarial vectors to the recommended insecticides of choice have posed an alarming situation in public health [3-5]. Both vectors and parasites of malaria have shown resistance selection pressure to insecticides and anti- malarial drugs respectively [4,6-10]. …”

Section: Introductionmentioning

confidence: 99%

Insecticidal activity of the essential oil from fruits and seeds of Schinus terebinthifolia Raddi against African malaria vectors

et al. 2011

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BackgroundAlternative insecticides for the control of malaria and filarial vectors are of paramount need as resistance is increasing among classes of insecticides currently in use in the public health sector. In this study, mosquitocidal activity of Schinus terebinthifolia essential oil against Anopheles gambiae s.s., An. arabiensis and Culex quinquefasciatus was assessed in laboratory, semi- field and full- field conditionsMethodTwenty third instar larvae of both Anopheles gambiae s.s. and Cx. quinquefasciatus were exposed to different dosages of plant extract in both laboratory and semi- field environments. Observation of the mortality response was assessed at intervals of 12, 24, 48 and 72 hours. Adult semi- gravid female mosquitoes were exposed to papers treated with S. terebinthifolia and compared with WHO standard paper treated with alphacypermethrin (0.05%).ResultsGas chromatography, coupled to mass spectrometry, identified 15 compounds from S. terebinthifolia extracts, the most abundant identified compound was δ-3-carene (55.36%) and the least was γ-elemene (0.41%). The density of the oil was found to be 0.8086 g/ml. The effective dosages in the insectary ranged from 202.15 to 2625.20 ppm and were further evaluated in the semi- field situation. In the laboratory, the mortality of Cx. quinquefasciatus ranged from 0.5 to 96.75% while for An. gambiae s.s it was from 13.75 to 97.91%. In the semi- field experiments, the mortality rates observed varied for both species with time and concentrations. The LC50 and LC95 value in the laboratory was similar for both species while in the semi- field they were different for each. In wild, adult mosquitoes, the KT50 for S. terebinthifolia was 11.29 minutes while for alphacypermethrin was 19.34 minutes. The 24 hour mortality was found to be 100.0% for S. terebinthifolia and 75.0% for alphacypermethrin which was statistically significant (P < 0.001).ConclusionThe efficacy shown by essential oils of fruits and seeds of S. terebinthifolia has given an opportunity for further investigation of individual components of these plant extracts and to evaluate them in small- scale field trials.

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Entomological survey and report of a knockdown resistance mutation in the malaria vector Anopheles gambiae from the Republic of Guinea

Cited by 14 publications

References 23 publications

Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa

Plasmodium falciparum infection rates for some Anopheles spp. from Guinea-Bissau, West Africa

Insecticide resistance in malaria vector mosquitoes at four localities in Ghana, West Africa

Insecticidal activity of the essential oil from fruits and seeds of Schinus terebinthifolia Raddi against African malaria vectors

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