Entrepreneurial orientation in different perspective contributes to the success of ventures differently. Therefore, this study aimed to investigate the contribution of entrepreneurial orientation towards the performance of small ventures in the context of different business sectors and the location of the businesses. To achieve this objective, the primary data was obtained from a sample of 210 small firms which were selected from the central part of Ethiopia using two level multi-stage sampling. The finding of the study indicates that entrepreneurial orientation positively influences ventures performance, but it will determine more when enterprises are established in city areas and involved in the industry sector. Therefore, the owner/ managers of enterprises should improve their practices of entrepreneurial orientation by introducing new lines, technologies, and market; improve workers' participation in developing new ideas and design; and compete aggressively by taking a calculated risk. Finally, our implication for further study is that future research has to compare the transited and failed enterprises in longitudinal studies to capture the progress of entrepreneurial orientation among transited and failed firms.