Envelhecimento pulmonar acelerado em pacientes com obesidade mórbida

Melo, Saulo Maia D'Ávila; Melo, Valdinaldo Aragão de; Melo, Enaldo Vieira de; Filho, Raimundo Sotero de Menezes; Castro, Vinicius Leite de; Barreto, Matheus Santana Paes

doi:10.1590/s1806-37132010000600012

Cited by 12 publications

(5 citation statements)

References 16 publications

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“…In a study aimed at evaluating the harm obesity can cause to lung function, Melo et al 22 found significant differences in FVC and FEV 1 between the obese and normal weight groups. The authors demonstrated pulmonary damage through the concept of lung age and found that this measure increases in patients with morbid obesity, suggesting early damage and accelerated lung aging in these individuals.…”

Section: Discussionmentioning

confidence: 99%

Influence of body mass index and age on the lung function of obese women

Sgariboldi

Faria

Carbinatto

et al. 2016

Rev. bras. geriatr. gerontol.

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Introduction: Obesity and aging may cause changes in lung function. Objective: to assess whether body mass, body mass index (BMI) and age influences vital capacity (VC) and forced expiratory volume in the first second (FEV 1 ) in women. Methods: 81 women aged between 30 and 75 years participated in the study. The sample included obese and morbidly obese, non-smoking, sedentary individuals without chronic lung disorders. Anamnesis, anthropometric and spirometric evaluations were performed. Statistical analysis was carried out using the Pearson correlation and Spearman tests, adopting a significance level of 5%. Results: It was observed that age had significant and negative correlations with VC and its components: inspiratory reserve volume (IRV), expiratory reserve volume (ERV) and tidal volume (TV), and with FEV 1 . There was also a significant positive correlation between body mass and VC and IRV and a significant negative correlation between BMI and ERV. Conclusion: Pulmonary function declines over time. Body mass appears to exert a greater influence on IRV, whereas a greater BMI is associated with a decline in ERV.

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Section: Discussionmentioning

confidence: 99%

Influence of body mass index and age on the lung function of obese women

Sgariboldi

Faria

Carbinatto

et al. 2016

Rev. bras. geriatr. gerontol.

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“…They understand that the diagnostic tool was comparable to the classical one and can be used in daily practice. Melo et al110 determined the lung age of patients with morbid obesity and compared it with the chronological age of these patients, emphasizing the premature damage that morbid obesity does to the lungs. Pereira et al111 evaluated the efficacy and safety of two inhalers for Mometasone furoate administration in patients with asthma and find that the use of the single-dose inhaler developed in Brazil is as effective and safe as is that of a standard inhaler in the treatment of patients with asthma.…”

Section: Introductionmentioning

confidence: 99%

A survey of recently published cardiovascular, hematological and pneumological original articles in the Brazilian scientific press

Patel¹,

Caramelli²,

Gomes³

2011

Clinics

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Recent original scientific contributions published in selected Brazilian periodicals and classifiable under cardiovascular and pulmonary subject categories cover a wide range of sub specialties, both clinical and exprimental. Because they appear in journals with only recently enhanced visibility, we have decided to highlight a number of specific items appeared in four Brazilian journals, because we understand that this is an important subsidy to keep our readership adequately informed. These papers cover extensive sub-areas in both fields.

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“…[248][249][250] Lung age was significantly older in patients with morbid obesity, severe airflow limitation, and COPD. [248][249][250][251]…”

Section: Lung Agementioning

confidence: 99%

Biomarkers of ageing: Current state‐of‐art, challenges, and opportunities

Chen

Wang

Zhang

et al. 2023

MedComm – Future Medicine

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Given the unprecedented phenomenon of population ageing, studies have increasing captured the heterogeneity within the ageing process. In this context, the concept of "biological age" has been introduced as an integrated measure reflecting the individualized ageing pace. Identifying reliable and robust biomarkers of age is critical for the accurate risk stratification of individuals and exploration into antiageing interventions. Numerous potential biomarkers of ageing have been proposed, spanning from molecular changes and imaging characteristics to clinical phenotypes. In this review, we will start off with a discussion of the development of ageing biomarkers, then we will provide a comprehensive summary of currently identified ageing biomarkers in humans, discuss the rationale behind each biomarker and highlight their accuracy and clinical value with a contemporary perspective. Additionally, we MedComm -Future Medicine.

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Envelhecimento pulmonar acelerado em pacientes com obesidade mórbida

Cited by 12 publications

References 16 publications

Influence of body mass index and age on the lung function of obese women

Influence of body mass index and age on the lung function of obese women

A survey of recently published cardiovascular, hematological and pneumological original articles in the Brazilian scientific press

Biomarkers of ageing: Current state‐of‐art, challenges, and opportunities

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