Environment induced self-aggregation behavior of κ-carrageenan/lysozyme complex

Xu, Wei; Jin, Weiping; Zhang, Chunlan; Liang, Hongshan; Shah, Bakht Ramin; Li, Bin

doi:10.1016/j.bcdf.2015.09.004

Cited by 5 publications

(1 citation statement)

References 37 publications

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“…These results suggest that DNA was distributed in the outer layer of particles and stabilized them in the aqueous solution. The complex particles of lysozyme/κ-carrageenan increased in size as their ratios increased [ 29 ]. The sizes of xanthan gum/lysozyme particles increased from 61.7 to 108 nm as their ratios changed from 3:1 to 1:3 [ 30 ].…”

Section: Resultsmentioning

confidence: 99%

Encapsulation of Folic Acid and α-Tocopherol in Lysozyme Particles and Their Bioaccessibility in the Presence of DNA

Gao²,

Cheng

et al. 2023

Antioxidants

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Protein particles have been reported as the potential carriers for the co-encapsulation of bioactive components. In this study, lysozyme, a basic protein, was used to simultaneously encapsulate folic acid and α-tocopherol at pH 4.0. The encapsulation efficiency and loading capacity of folic acid or α-tocopherol increased with its respective concentration. Folic acid had no influence on the encapsulation of α-tocopherol. However, the encapsulation of folic acid was improved by α-tocopherol below 40 μg/mL but reduced by α-tocopherol at higher concentrations. The encapsulation by lysozyme shielded folic acid, α-tocopherol, or both partially from the attack of 2,2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical cation. No masking effect of lysozyme encapsulation on α-tocopherol was found in DPPH antioxidant activity assay. Furthermore, the DNA coating was used to improve the dispersion of lysozyme with folic acid and α-tocopherol. The lysozyme/DNA particles with folic acid and α-tocopherol showed a homogenous size distribution of 180–220 nm with ζ-potential values between −33 and −36 mV. The release and bioaccessibility of folic acid in lysozyme/DNA with α-tocopherol were similar to that of folic acid alone, while the release of α-tocopherol was delayed and its bioaccessibility was improved by encapsulation in lysozyme/DNA with folic acid. The data gathered here would provide guidance for the use of lysozyme-based co-encapsulating carriers in the development of functional foods.

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Section: Resultsmentioning

confidence: 99%