Environmental and Safety Issues With Nanoparticles

Makino, Hisao; Emi, Hitoshi; Yamaguchi, Akimasa; Iritani, Eiji; Namiki, Norikazu; Myojo, Toshihiko; Yamamoto, Kenji

doi:10.1016/b978-044453122-3.50010-6

Cited by 5 publications

(5 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Utilizing the MTT test, we delved into evaluating the potential impact of Stevia extract, a process that hinges on assessing mitochondrial metabolism and its implications [27]. Ranging from 0.01 to 1 mg/mL, the aqueous Stevia extract was introduced to the HDF cell line to discern its effects on cellular viability.…”

Section: -[45- Dimethylthiazol-2-yl]-2 5 Diphenyltetrazolium Bromide ...mentioning

confidence: 99%

“…Cells treated with 0.5 and 1 mg/mL of the extract showcased a viability of roughly 80%, juxtaposed against the control group (p > 0.01). Strikingly, the cells retained their Utilizing the MTT test, we delved into evaluating the potential impact of Stevia extract, a process that hinges on assessing mitochondrial metabolism and its implications [27].…”

Section: -[45- Dimethylthiazol-2-yl]-2 5 Diphenyltetrazolium Bromide ...mentioning

confidence: 99%

See 1 more Smart Citation

Unlocking the Therapeutic Potential of Stevia rebaudiana Bertoni: A Natural Antiglycating Agent and Non-Toxic Support for HDF Cell Health

Shahu,

Kumar,

Ali

et al. 2023

Molecules

View full text Add to dashboard Cite

Sugar carbonyl groups interact with protein amino groups, forming toxic components referred to as advanced glycation end products (AGEs). The glycation system (BSA, a model protein, and fructose) was incubated for five weeks at 37 °C in the presence and absence of Stevia leaf extract. The results indicated that the leaf extract (0.5 mg/mL) decreased the incidence of browning (70.84 ± 0.08%), fructosamine (67.27 ± 0.08%), and carbonyl content (64.04 ± 0.09%). Moreover, we observed an 81 ± 8.49% reduction in total AGEs. The inhibition of individual AGE (argpyrimidine, vesper lysine, and pentosidine) was ~80%. The decrease in the protein aggregation was observed with Congo red (46.88 ± 0.078%) and the Thioflavin T (31.25 ± 1.18%) methods in the presence of Stevia leaf extract. The repercussion of Stevia leaf extract on DNA glycation was examined using agarose gel electrophoresis, wherein the DNA damage was reversed in the presence of 1 mg/mL of leaf extract. When the HDF cell line was treated with 0.5 mg/mL of extract, the viability of cells decreased by only ~20% along with the same cytokine IL-10 production, and glucose uptake decreased by 28 ± 1.90% compared to the control. In conclusion, Stevia extract emerges as a promising natural agent for mitigating glycation-associated challenges, holding potential for novel therapeutic interventions and enhanced management of its related conditions.

show abstract

Section: -[45- Dimethylthiazol-2-yl]-2 5 Diphenyltetrazolium Bromide ...mentioning

confidence: 99%

Section: -[45- Dimethylthiazol-2-yl]-2 5 Diphenyltetrazolium Bromide ...mentioning

confidence: 99%

Unlocking the Therapeutic Potential of Stevia rebaudiana Bertoni: A Natural Antiglycating Agent and Non-Toxic Support for HDF Cell Health

Shahu,

Kumar,

Ali

et al. 2023

Molecules

View full text Add to dashboard Cite

show abstract

“…To assess the biocompatibility of the 3B/GE/PCL sample, an MTT assay was performed. MTT assays provide a quantitative assessment of the cellular response to the surface of coated substrates [55][56][57]. The results of cell viability illustrated in Figure 7 were determined by the cell counting method [58].…”

Section: Mtt Analysismentioning

confidence: 99%

Surface Modification of 316L SS Implants by Applying Bioglass/Gelatin/Polycaprolactone Composite Coatings for Biomedical Applications

et al. 2020

View full text Add to dashboard Cite

In this study, various composites of bioglass/gelatin/polycaprolactone (BG/GE/PCL) were produced and coated on the surface of 316L stainless steel (SS) to improve its bioactivity. X-ray diffractometry (XRD), scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) were utilized to characterize the specimens. The results showed that bioglass particles were distributed uniformly in the coating. By increasing the wt.% of bioglass in the nanocomposite coatings, the surface roughness and adhesion strength increased. The corrosion behavior of GE/PCL (PCL-10 wt.% gelatin coated on 316L SS) and 3BG/GE/PCL (GE/PCL including 3 wt.% bioglass coated on 316L SS) samples were studied in PBS solution. The results demonstrated that 3BG/GE/PCL sample improved the corrosion resistance drastically compared to the GE/PCL specimen. In vitro bioactivity of samples was examined after soaking the specimens for 7, 14 and 28 days in simulated body fluid (SBF). The results showed a significant apatite formation on the surface of 3BG/GE/PCL samples. The cell viability evaluation was performed using 3- (4, 5-dimethylthiazol-2-yl)-2,5 diphenyltetrazoliumbromide (MTT) tests which confirmed the enhanced cell viability on the surface of 3BG/GE/PCL samples. The in vivo behavior of specimens illustrated no toxicity and inflammatory response and was in a good agreement with the results obtained from the in vitro test.

show abstract

“…8,9 During the CMP process, a large volume of ultrapure water is used to clean the surface of polishing substrate (e.g., wafers), generating wastewater containing NM from the CMP slurry. 10 Thus CMP wastewater is potentially a major source of NM into sewer systems, and eventually into the environment. However, essentially no data exist on these materials because Si, Ce, and Al are not regulated metals in industrial discharges or at municipal wastewater treatment plants (WWTPs).…”

Section: Introduction To Nanomaterials In Chemical Mechanical Polishimentioning

confidence: 99%

Control of Nanomaterials Used in Chemical Mechanical Polishing/Planarization Slurries during On-site Industrial and Municipal Biological Wastewater Treatment

Bi¹,

Reed²,

Westerhoff³

2015

Characterization of Nanomaterials in Complex Environmental and Biological Media

View full text Add to dashboard Cite

Environmental and Safety Issues With Nanoparticles

Cited by 5 publications

References 81 publications

Unlocking the Therapeutic Potential of Stevia rebaudiana Bertoni: A Natural Antiglycating Agent and Non-Toxic Support for HDF Cell Health

Unlocking the Therapeutic Potential of Stevia rebaudiana Bertoni: A Natural Antiglycating Agent and Non-Toxic Support for HDF Cell Health

Surface Modification of 316L SS Implants by Applying Bioglass/Gelatin/Polycaprolactone Composite Coatings for Biomedical Applications

Control of Nanomaterials Used in Chemical Mechanical Polishing/Planarization Slurries during On-site Industrial and Municipal Biological Wastewater Treatment

Contact Info

Product

Resources

About