2013
DOI: 10.1007/s11356-013-1748-0
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Environmental factors and unhealthy lifestyle influence oxidative stress in humans—an overview

Abstract: Oxygen is the most essential molecule for life; since it is a strong oxidizing agent, it can aggravate the damage within the cell by a series of oxidative events including the generation of free radicals. Antioxidative agents are the only defense mechanism to neutralize these free radicals. Free radicals are not only generated internally in our body system but also trough external sources like environmental pollution, toxic metals, cigarette smoke, pesticides, etc., which add damage to our body system. Inhalin… Show more

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Cited by 188 publications
(131 citation statements)
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“…Another endogenous resource of ROS is inflammatory reaction, such as release of ROS by polymorpho-nuclear leukocytes and macrophage peroxisomes. Exogenous sources of ROS include smoke, air pollution, and pesticides [3,4]. ROS has important roles in the body, including its involvement in the signal transduction of inflammation to resist pathogen infection [5].…”
Section: Introductionmentioning
confidence: 99%
“…Another endogenous resource of ROS is inflammatory reaction, such as release of ROS by polymorpho-nuclear leukocytes and macrophage peroxisomes. Exogenous sources of ROS include smoke, air pollution, and pesticides [3,4]. ROS has important roles in the body, including its involvement in the signal transduction of inflammation to resist pathogen infection [5].…”
Section: Introductionmentioning
confidence: 99%
“…Several evidences also suggest that interactions between genetic and environmental factors confer the multifaceted disease phenotypes of POAG [29,30]. This suggests that individuals carrying POAG-associated genetic polymorphisms might be more predisposed to the development of the disease when they are exposed to specific environmental factors like atmospheric pollutants, cigarette smoke, ultraviolet rays and radiation, by creating an imbalance between pro-oxidants and antioxidants, leading to oxidative stress [31].…”
Section: Discussionmentioning
confidence: 99%
“…Organizm człowieka narażony jest również na zwiększenie generowania RFT na skutek ekspozycji na promieniowanie UV lub w wyniku metabolizmu ksenobiotyków [2]. Do nasilonego tworzenia RFT, prowadzącego do stresu oksydacyjnego, dochodzi ponadto w przebiegu procesów zapalnych towarzyszących różnorodnym schorzeniom, np.…”
Section: Wego (Ounclassified