Environmental stress during larval development induces DNA methylation shifts in the migratory painted lady butterfly (<i>Vanessa cardui</i>)

Boman, Jesper; Zhu, Yishu; Höök, Lars; Vila, Roger; Talavera, Gerard; Backström, Niclas

doi:10.1111/mec.16957

Cited by 6 publications

(2 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Variation in migratory behaviour is likely a response to multiple environmental cues such as resource availability, photoperiod, temperature, humidity, and host plant quality. Recent experiments have demonstrated differences in V. cardui gene expression, methylation, and gene regulation due to the density of larval conspecifics, larval food availability, and host plant availability for oviposition (78,79), suggesting a strong response to environmental cues. The transcriptional basis of differences in migration distance has been explored in the moth Helicoverpa armigera and in D. plexippus , yielding promising candidate genes (59,80).…”

Section: Discussionmentioning

confidence: 99%

Isotope geolocation and population genomics inVanessa cardui:Short- and long-distance migrants are genetically undifferentiated

Reich,

Shipilina,

Talla

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

The painted lady butterflyVanessa carduiis renowned for its virtually cosmopolitan distribution and the remarkable long-distance migrations that are part of its annual, multi-generational migratory cycle. In the autumn,V. carduiindividuals are found north and south of the Sahara, suggesting distinct migratory behaviours within the species. However, the evolutionary and ecological factors shaping these differences in migratory behaviour remain largely unexplored. Here, we performed whole-genome resequencing and analysed the hydrogen and strontium isotopic signatures of 40V. carduiindividuals simultaneously collected in the autumn from regions both north and south of the Sahara. Our investigation revealed two main migratory groups: (i) short-distance migrants, journeying from temperate Europe to the circum-Mediterranean region and (ii) long-distance migrants, originating from temperate Europe, crossing the Mediterranean Sea and Sahara, and reaching West Africa, covering a distance of up to over 4,000 km. Despite these stark differences in migration distance, a genome-wide analysis of 813,810 single nucleotide polymorphisms (SNPs) revealed that both short- and long-distance migrants belong to a single intercontinental panmictic population extending from northern Europe to sub-Saharan Africa. Contrary to common biogeographic patterns, the Sahara is not a catalyst for population substructuring in this species. No significant genetic differentiation or signs of adaptation and selection were observed between the two migratory phenotypes (pairwise FST= 0.001 ± 0.006). Nonetheless, two individuals, belonging to the early arrivals to the Afrotropical region and covering longer migration distances, exhibited some genetic differentiation. The lack of genetic structure between short- and long-distance migrants suggests that migration distance inV. carduiis a plastic response to environmental conditions.

show abstract

Section: Discussionmentioning

confidence: 99%

Isotope geolocation and population genomics inVanessa cardui:Short- and long-distance migrants are genetically undifferentiated

Reich,

Shipilina,

Talla

et al. 2023

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…Common to these mechanisms is that they are all predicted to yield a negative relationship between the level of DNA methylation in the promoter region and expression level. Gene body methylation on the other hand shows (if any) a positive or quadratic relationship with expression level, but the function of gene body methylation is debated [ 23 – 27 ].…”

Section: Introductionmentioning

confidence: 99%

Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring F1 hybrids

Boman,

Qvarnström,

Mugal

2024

BMC Biol

Self Cite

View full text Add to dashboard Cite

Background Regulation of transcription by DNA methylation in 5’-CpG-3’ context is a widespread mechanism allowing differential expression of genetically identical cells to persist throughout development. Consequently, differences in DNA methylation can reinforce variation in gene expression among cells, tissues, populations, and species. Despite a surge in studies on DNA methylation, we know little about the importance of DNA methylation in population differentiation and speciation. Here we investigate the regulatory and evolutionary impact of DNA methylation in five tissues of two Ficedula flycatcher species and their naturally occurring F1 hybrids. Results We show that the density of CpG in the promoters of genes determines the strength of the association between DNA methylation and gene expression. The impact of DNA methylation on gene expression varies among tissues with the brain showing unique patterns. Differentially expressed genes between parental species are predicted by genetic and methylation differentiation in CpG-rich promoters. However, both these factors fail to predict hybrid misexpression suggesting that promoter mismethylation is not a main determinant of hybrid misexpression in Ficedula flycatchers. Using allele-specific methylation estimates in hybrids, we also determine the genome-wide contribution of cis- and trans effects in DNA methylation differentiation. These distinct mechanisms are roughly balanced in all tissues except the brain, where trans differences predominate. Conclusions Overall, this study provides insight on the regulatory and evolutionary impact of DNA methylation in songbirds.

show abstract

Pollen metabarcoding reveals the origin and multigenerational migratory pathway of an intercontinental-scale butterfly outbreak

Gorki,

López-Mañas,

Sáez

et al. 2024

Current Biology

View full text Add to dashboard Cite

Environmental stress during larval development induces DNA methylation shifts in the migratory painted lady butterfly (Vanessa cardui)

Cited by 6 publications

References 81 publications

Isotope geolocation and population genomics inVanessa cardui:Short- and long-distance migrants are genetically undifferentiated

Isotope geolocation and population genomics inVanessa cardui:Short- and long-distance migrants are genetically undifferentiated

Regulatory and evolutionary impact of DNA methylation in two songbird species and their naturally occurring F1 hybrids

Pollen metabarcoding reveals the origin and multigenerational migratory pathway of an intercontinental-scale butterfly outbreak

Contact Info

Product

Resources

About