2014
DOI: 10.1136/archdischild-2013-305444
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Environmental tobacco smoke exposure and risk of allergic sensitisation in children: a systematic review and meta-analysis

Abstract: Current analysis supports an association between ETS exposure in early childhood and the increased risk of allergic sensitisation. Subgroup meta-analyses demonstrate that younger children suffer the most from detrimental immunomodulating effects of ETS exposure. This study underscores ETS as an important but avoidable risk factor for the development of allergic disease in children.

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Cited by 70 publications
(44 citation statements)
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“…Numerous past and recent studies have documented the adverse health effects of environmental tobacco smoke (ETS; Castro et al 2011;Wu et al 2012;McCarville et al 2013;Feleszko et al 2014). Following the enhancement of regulatory measures on tobacco consumptions in public spaces, the tobacco industry initiated major investments in the development of new products, in an effort to revive the business by promoting and marketing new (often unregulated) products for the consumers (Savell et al 2014).…”
Section: Introductionmentioning
confidence: 99%
“…Numerous past and recent studies have documented the adverse health effects of environmental tobacco smoke (ETS; Castro et al 2011;Wu et al 2012;McCarville et al 2013;Feleszko et al 2014). Following the enhancement of regulatory measures on tobacco consumptions in public spaces, the tobacco industry initiated major investments in the development of new products, in an effort to revive the business by promoting and marketing new (often unregulated) products for the consumers (Savell et al 2014).…”
Section: Introductionmentioning
confidence: 99%
“…The World Health Organization estimated that each year ETS exposure is responsible for more than 890,000 premature deaths worldwide [4]. ETS exposure during childhood has been linked to an increased risk of sudden infant death syndrome [5] and allergic sensitization [6] in addition to the development of asthma [7,8]. Moreover, children with long-term ETS exposure are more susceptible to upper and lower respiratory tract infections, reduced lung function and/ or early onset of cardiovascular diseases [7,8].…”
Section: Introductionmentioning
confidence: 99%
“…In childhood, secondhand smoke is linked to childhood asthma, allergies, reduced lung function, recurrent otitis media, and attention-deficit/hyperactivity disorder (ADHD). [31][32][33]37,38 Evidence suggests a relationship between prenatal and postnatal exposure to ETS and the development of childhood cancers such as brain tumors, leukemia, and lymphoma. Further research is warranted to further investigate this association.…”
Section: Toxic Effectsmentioning
confidence: 99%