Environmental Toxins and the Heart

Rahnama‐Moghadam, Sahand; Hillis, L. David; Lange, Richard A.

doi:10.1016/b978-0-12-416595-3.00003-7

Cited by 5 publications

(3 citation statements)

References 497 publications

(366 reference statements)

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“…Additionally, in South Asia, cardenolides from pink, white or yellow oleander are a leading cause of poisoning, including for suicide, with thousands of cases a year and a fatality rate from 5% to 10% [41]. Accidental poisoning also occurs by inhaling toxic fumes, due to the use of parts of the plant as firewood for a barbecue [42].…”

Section: Introductionmentioning

confidence: 99%

A Probable Fatal Case of Oleander (Nerium oleander) Poisoning on a Cattle Farm: A New Method of Detection and Quantification of the Oleandrin Toxin in Rumen

Rubini

Rossi

Mestria

et al. 2019

Toxins

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Oleander (Nerium oleander) is an ornamental plant common in tropical and sub-tropical regions that is becoming increasingly widespread, even in temperate regions. Oleander poisoning may occur in animals and humans. The main active components contained in the plant are cardiac glycosides belonging to the class of cardenolides that are toxic to many species, from human to insects. This work describes a case of oleander poisoning that occurred on a small cattle farm and resulted in the fatality of all six resident animals. Furthermore, the investigation of the poisonous agent is described, with particular focus on the characterization of the oleandrin toxin that was recovered from the forage and rumen contents. The innovation of this study is the first description of the detection and quantification of the oleandrin toxin by liquid chromatography-high resolution mass spectrometry (LC-HRMS) in rumen.

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Section: Introductionmentioning

confidence: 99%

A Probable Fatal Case of Oleander (Nerium oleander) Poisoning on a Cattle Farm: A New Method of Detection and Quantification of the Oleandrin Toxin in Rumen

Rubini

Rossi

Mestria

et al. 2019

Toxins

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“…Insects that are resistant to Cardenolides have developed cardenolide insensitive Na + K + ATPase (e.g., the caterpillar of the monarch butterfly which feeds exclusively on the leaves of Calotropis). [ 3 ] Our current understanding is that the Calotropin biosynthesis is similar to that of Digoxin. Other commonly used plant toxin for deliberate self-harm Oleander also contains Cardenolides.…”

Section: Discussionmentioning

confidence: 99%

Calotropis poisoning with severe cardiac toxicity A case report

Iyadurai

Gunasekaran

Jose

et al. 2020

J Family Med Prim Care

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Calotropis is a widely prevalent plant in the Indian Subcontinent. The extract and various parts of the plant are used by traditional healers for treating miscellaneous diseases. All parts of the plants are toxic; there are many case reports of gastrointestinal, cutaneous and ocular toxicity with Calotropis. The plant contains Cardenolide glycosides which have Digoxin like effects and can cause severe cardiotoxicity. We report a patient who developed cardiovascular collapse after oral ingestion and cutaneous application of Calotropis following snake bite by a traditional healer, this case thus highlights the potential cardiotoxicity of Calotropis.

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“…Natural gas is considered sour when the H2S gas is approximately more than 4 ppm by volume under standard temperature and pressure [4]. It presents major problem due to its high toxicity, flammability, explosivity and corrosivity [5][6][7][8][9]. Therefore, it is very important to remove H2S from the gas stream or alternatively, converting it into a lesser hazardous and more valuable material such as elemental sulfur.…”

Section: Introductionmentioning

confidence: 99%

Formulation of Catalytic Deep Eutectic Solvent for H2S Oxidative Absorption at Ambient Condition with Assistance of Cosmo-Rs

Nor Fariza Abd Mutalib,

Muhammad Shazwan Shabani,

Mohamad Azmi Bustam

2024

ARASET

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H2S is very well known for its toxicity, corrosivity, flammability and explosiveness which in overall lead to operational difficulty. Hence, raising the need for H2S sweetening process. However, the current conventional sweetening process is very energy intensive besides suffer from catalyst deactivation issue. Therefore, raising the need for more environmentally and economical friendly approach such as utilizing green solvent like deep eutectic solvent. Thus, the objective of this research is to determine the best combination of HBD and HBA components for catalytic DESs to convert H2S at room temperature. The study utilized COSMO-RS computational to assist in selecting the appropriate components, synthesized and characterized the chosen catalytic DES, and performed oxidative absorption of H2S using the selected DES. Initially, the solubility and selectivity performance of various HBD and HBA were evaluated, and the components with the best performance were combined with CuCl2.2H2O to form catalytic DES. The synthesized catalytic DES was characterized using FTIR and tested for its oxidation absorption capability. Based on the COSMO-RS screening, 1-butyl-3-methylimidazoilum chloride [bmim][Cl] and ethylene glycol [EG] were determined to be the best HBD and HBA, respectively. The catalytic DES formed from these components was homogeneous and brown in colour. The results of oxidative absorption showed that the catalytic DES rapidly produced a yellow precipitate, which was later confirmed to be sulphur. The study concludes that COSMO-RS computational can be used to formulate DESs for H2S oxidative absorption, and catalytic DES maintained its properties before and after H2S oxidation. The research also suggests that oxidative absorption of H2S to sulphur using catalytic DESs is a feasible and rapid.

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Environmental Toxins and the Heart

Cited by 5 publications

References 497 publications

A Probable Fatal Case of Oleander (Nerium oleander) Poisoning on a Cattle Farm: A New Method of Detection and Quantification of the Oleandrin Toxin in Rumen

A Probable Fatal Case of Oleander (Nerium oleander) Poisoning on a Cattle Farm: A New Method of Detection and Quantification of the Oleandrin Toxin in Rumen

Calotropis poisoning with severe cardiac toxicity A case report

Formulation of Catalytic Deep Eutectic Solvent for H2S Oxidative Absorption at Ambient Condition with Assistance of Cosmo-Rs

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