Environmentally benign synthesis of sydnone containing 1,3,4-thiadiazines under microwave and solvent-free conditions

Abstract

Novel, convenient and benign synthesis of 2-arylamino-5-(3′-arylsydnone-4-yl)-1,3,4-thiadiazines 3a-l by the interaction of 3-substituted-4-bromoacetyl sydnones 1 with substituted thiosemicarbazides 2 under MW irradiation and solvent-free condition is described.

Synthesis, characterization and biological evaluation of dihydropyrimidine derivatives

“…Prompted by these observations and in continuation of our search for green technique (Hegde et al, 2007;Priya et al, 2007;Rai et al, 2009;Gowda et al, 2010) we herein report the synthesis of title compounds using microwave (MW) energy. Recently a major development that had a profound impact on heterogeneous reactions is the use of MW irradiation techniques.…”

Studies in the Antimicrobial Activities of Some Newly Synthesized Triazines by Disc Diffusion Method and Mic Methods

“…[6] Hence it was thought interesting to carry out the antimicrobial activities against various microbes to check the drug properties of newly synthesized 1,3,5-triazines by Disc diffusion method and MIC methods in this laboratory. [7,8,9,10] …”

Studies in the Antimicrobial Activities of Some Newly Synthesized [1,4] Substituted Benzodiazepines by Disc Diffusion Method and MIC Methods

“…Recently new series of 1,2,4-thiadiazoles, 1,3,5-thiadiazines and 1,3,5-dithiazines were synthesized by exploring the synthetic applications of -thiocarbamido, -amino, -halo, -cyano, etc. and their antimicrobial, antifungal, antibacterial, analgesic physiochemical parameters [7][8][9][10] were studied. Hence it was thought interesting to carry out the antimicrobial activities against various microbes to check the drug properties of newly synthesized 1,4-substituedbenzodiazepines by Disc diffusion method and MIC methods in this laboratory.…”