Enzymatic determination of sorbic acid

Hofer, K.; Jenewein, D

doi:10.1007/s002170050591

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2002

2020

Publication Types

Select...

Book4

Article1

Relationship

Self Cite0

Independent5

Authors

Journals

Cited by 7 publications

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Determination of azelaic and sorbic acid in pharmaceduticals by capillary electrophoresis

et al. 2002

View full text Add to dashboard Cite

SummaryCapillary electrophoresis with indirect UV detection at 254 nm was applied to simultaneous determination of ~ 20% of azelaic acid and ~ 0.1% of sorbic acid in AKNOREN cream. The acids were separated in fused silica capillary (45 cm x 50 gm) at 30 kV. Optimised background electrolyte was 30 mM benzoate buffer (pH ~ 6, adjusted with TRIS) containing 7 mM 13-cyclodextrin and 5% of methanol; internal standard was 2-hydroxyisobutyric acid (HIBA). Rectilinear calibration ranges were 0.4-4 mg mL 1 for azelaic acid and 2-20 gg mL 1 for sorbic acid and the recoveries were 97.2 -100.5%. A single analysis took < 15 min.

show abstract