Enzyme histochemical studies of human gastric and jejunal biopsy specimens in normal and disease states

Intracellular enzymatic histochemistry of the human stomach with special reference to atrophic gastritis.

“…Niemi, Siurala, and Larmi (1961) also found the same distribution of oxidative enzymes in the metaplastic cells as in small bowel mucosa. Other investigators (Cornet, Bescol-Liversac, Guillam, and Debussche, 1962;Plosscowe, Berg, and Segal, 1963) subsequently confirmed the increased alkaline phosphatase activity in the brush border of the metaplastic epithelium.…”

Functional histochemistry of the small bowel mucosa in malabsorptive syndromes

“…Review of Bolt's published photographs, however, suggests that the reaction is of normal intensity over the surface epithelium and that it is decreased in extent only by shortening and fusing of the villi. Plosscowe, Berg, and Segal (1963) have recently recorded normal trimetaphosphate and alkaline phosphatase activity in the epithelium of the bowel in idiopathic steatorrhoea.…”

Alkaline phosphatase levels in normal and diseased small bowel.

“…They stated that enzyme activity was diminished in patients with 'primary sprue'. Plosscowe, Berg, and Segal (1963), also using a histological technique, found no significant difference in alkaline phosphatase activity between the jejunal biopsy specimens of 20 normals, 10 patients with primary malabsorption (nontropical sprue), and two with pernicious anaemia.…”