Celiac Disease - From Pathophysiology to Advanced Therapies 2012
DOI: 10.5772/50247
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Enzyme Therapy for Coeliac Disease: Is It Ready For Prime Time?

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Cited by 2 publications
(2 citation statements)
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References 78 publications
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“…Stepniak et al (2006) have identified a prolyl endopeptidase from Aspergillus niger that is able to degrade T-cell stimulatory peptides in vitro. It is also suspected that caricain, which contains endopeptidases, can achieve detoxification by digestion of immunoactive fragments of gluten (Cornell & Stelmasiak, 2007, 2012.…”
Section: Introductionmentioning
confidence: 98%
“…Stepniak et al (2006) have identified a prolyl endopeptidase from Aspergillus niger that is able to degrade T-cell stimulatory peptides in vitro. It is also suspected that caricain, which contains endopeptidases, can achieve detoxification by digestion of immunoactive fragments of gluten (Cornell & Stelmasiak, 2007, 2012.…”
Section: Introductionmentioning
confidence: 98%
“…The results of these experiments are promising and add to the body of knowledge gained from mucosal digestion of natural and synthetic peptides and the use of caricain for supplementary digestion of the gliadin (Cornell & Stelmasiak, 2012). It must be understood that the immunoassay results are not necessarily related to toxicity in the same way as the results of the lysosome assay.…”
Section: Reduction In Absorbance (%)mentioning
confidence: 87%