Eosinophilic esophagitis: An increasingly recognized cause of dysphagia, food impaction, and refractory heartburn

Abstract

Eosinophilic esophagitis is an increasingly recognized cause of a variety of esophageal symptoms, including dysphagia, food impaction, atypical chest pain, and heartburn that does not respond to medical therapy. Its cause is unknown, but allergic and immune-mediated mechanisms similar to those of asthma and other atopic diseases are implicated.

Infective Esophagitis: Inhaled Steroids Treatment for Eosinophilic Esophagitis not Always Safe

“…Eosinophilic esophagitis is an immune-mediated disease affecting the esophagus with increasing recognition and prevalence [1]. It is characterized histologically by eosinophilpredominant inflammation of the esophagus [2].…”

Quantifying Human Eosinophils Using Three-Dimensional Volumetric Images Collected With Multiphoton Fluorescence Microscopy

“…Eosinophilic esophagitis (EoE) is a relatively new disease with ~10-fold increase in prevalence over the past 20 years, 1,2 and has been found in ~6.5% of the population undergoing upper endoscopy. 3 This disease has become one of the leading causes of dysphagia and food impaction in adults.…”

Clinical Case Report of PPI-refractory Gastro-Esophageal Reflux Disease (GERD) with Korean Medicine Treatment - A Focus on Evaluation of the Abdominal Examination

“…Eosinophilic esophagitis is an increasingly common cause of GER symptoms and dysphagia. Because esophageal intramucosal eosinophilia is a frequent finding associated with GERD, lack of histological response to high-dose PPIs should be considered before making the final diagnosis (21)(22)(23). On the other hand, in recent years, a form of esophageal eosinophilia has been recognized that responds to PPI therapy.…”