Eosinophilic gastroenteritis: Clinical manifestations and morphological characteristics, a retrospective study of 42 patients

Zhang, Li; Duan, Liping; Ding, Shigang; Lu, Jingjing; Jin, Zhu; Cui, Rong; McNutt, Michael A.; Wang, Aiying

doi:10.3109/00365521.2011.579998

Cited by 88 publications

(82 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The most common endoscopic finding of EGE includes mucosal hyperemia, and erythema. 8 However erosions, superficial ulcers, or nodularity can also be seen as in our patient. The characteristic histologic findings reveal eosinophilic infiltration of the mucosal lamina propria and eosinophil-mediated epithelial injury.…”

Section: Discussionsupporting

confidence: 66%

“…8 Our patient had prior endoscopies with biopsies with no evidence of eosinophilic colitis or of eosinophilic esophagitis. The most common endoscopic finding of EGE includes mucosal hyperemia, and erythema.…”

Section: Discussionmentioning

confidence: 77%

“…8 Peripheral eosinophilia or an increased IgE level may also be found in parasitic infection, allergic disorders, or lymphoma. However in patients with peripheral eosinophilia in the setting of underlying EGE, the clue to the presence of a parasitic infection was a sudden worsening of symptoms and concurrent tissue eosinophilia as in our patient.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Isospora belli superinfection in a patient with eosinophilic gastroenteritis—A diagnostic challenge

Navaneethan

Venkatesh

Downs‐Kelly

et al. 2012

Journal of Crohn's and Colitis

View full text Add to dashboard Cite

Isospora belli infection, characterized by peripheral blood eosinophilia, is often seen as an opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS). It is also reported in patients with underlying lymphoproliferative disorders including lymphoma and leukemia. Eosinophil-associated gastrointestinal disorders (EGID), including eosinophilic gastroenteritis (EGE), is characterized by eosinophilic infiltration of the gastrointestinal (GI) tract with various GI symptoms. We report a case of a 50-year-old male who developed Isospora superinfection of the small bowel while receiving systemic corticosteroids for EGE. He presented with worsening diarrhea, abdominal pain, nausea and vomiting with worsening peripheral eosinophilia. I. belli infection was diagnosed by the detection of oocysts in stool samples and by the presence of the parasite on duodenal biopsy in the background of tissue eosinophilia. I. belli can cause severe chronic diarrhea in immunocompromised patients on corticosteroids. Trimethoprim-sulfamethoxazole often provided rapid cure. Even though peripheral blood eosinophilia was seen in both EGE and Isospora infection, the identification of subnuclear protozoal inclusions as a new histologic finding, as well as the absence of this finding in previous duodenal biopsies coupled with the continued presence of tissue eosinophilia, favored a parasitic superinfection in the setting of underlying EGE.

show abstract

Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 77%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Isospora belli superinfection in a patient with eosinophilic gastroenteritis—A diagnostic challenge

Navaneethan

Venkatesh

Downs‐Kelly

et al. 2012

Journal of Crohn's and Colitis

View full text Add to dashboard Cite

show abstract

“…Since eosinophilic infiltration may be observed in many conditions including gastroesophageal reflux disease, parasitic contamination and inflammatory bowel disease, the diagnosis of eosinophilic gastropathy should be considered after the other possibilities are excluded (9,10). The diagnostic criteria of eosinophilic gastroenteritis include gastrointestinal symptoms, eosinophilic infiltration in one or more areas which can be demonstrated by biopsy, absence of any involvement outside the gastrointestinal tract and absence of parasitic contamination (9,10). There is no atopic history in approximately half of the patients (10).…”

Section: Discussionmentioning

confidence: 99%

“…The diagnostic criteria of eosinophilic gastroenteritis include gastrointestinal symptoms, eosinophilic infiltration in one or more areas which can be demonstrated by biopsy, absence of any involvement outside the gastrointestinal tract and absence of parasitic contamination (9,10). There is no atopic history in approximately half of the patients (10). Frequently, there is a strong familial history of food allergy.…”

Section: Discussionmentioning

confidence: 99%

Does bee pollen cause to eosinophilic gastroenteropathy?

et al. 2015

View full text Add to dashboard Cite

Bee pollen is given to children by mothers in order to strengthen their immune systems. There are no studies related with the side effects of bee polen in the literature. In this article, the literature was reviewed by presenting a case of allergic eosinophilic gastropathy related with bee polen. A 5-year old child was admitted due to abdominal pain. Edema was detected on the eyelids and pretibial region. In laboratory investigations, pathology was not detected in terms of hepatic and renal causes that would explain the protein loss of the patient diagnosed with hypoproteinemia and hypoalbuminemia. Urticaria was detected during the follow-up visit. When the history of the patient was deepened, it was learned that bee pollen was given to the patient every day. The total eosinophil count was found to be 1 800/mm 3 . Allergic gastroenteropathy was considered because of hypereosinophilia and severe abdominal pain and endoscopy was performed. Biopsy revealed abundant eosinophils in the whole gastric mucosa. A diagnosis of allergic eosinophilic gastropathy was made. Bee polen was discontinued. Abdominal pain and edema disappeared in five days. Four weeks later, the levels of serum albumin and total eosinophil returned to normal. (Turk Pediatri Ars 2015; 50: 189-92)

show abstract