Eosinophilic Granuloma of the Mandible

Abstract

Eosinophilic granuloma is the most benign and common form of the Langerhans cell histiocytosis, a rare proliferative disease that can affect single or multiple organs. In the quite common head and neck manifestation these lesions can be confused in the beginning, with other bone diseases such as odontogenic cysts, periodontal disease, or malignancies. Treatment varies depending on the size, number, localization of the lesions, and patient's general conditions. The authors describe here a patient of a single lesion of eosinophilic granuloma localized in the posterior mandible region treated with a very conservative surgical approach in a patient with poor socio-economic conditions. The authors performed teeth extractions, an excisional biopsy and open curettage and after a follow-up of 24 months without partial mandible resection and reconstruction time the lesion had healed. The clinical situation confirmed that, in carefully selective patients, a conservative approach could be a useful therapeutic opportunity.

Multidisciplinary rehabilitation of eosinophilic granuloma with bone graft surgery and a modified implant‐supported hybrid prosthesis: A case report with a 6‐year follow‐up

“…Recurrence rate depends upon the degree of tissue involvement and the treatment method opted; hence, the patient must be monitored closely for a long period . Fiorini et al reported a case with a single EG lesion treated with a very conservative surgical approach with no recurrence during a 2‐year follow‐up period. This approach only consisted of excision of the lesion and curettage of the residual cavity.…”