Epidemiologic Approaches for Assessing Health Risks from Complex Mixtures in Indoor Air

Samet, Jonathan M.; Lambert, William E.

doi:10.2307/3431109

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…relationship between ventilation systems and health scientifically problematic (30,33). Among the SBS symptoms, we included those that can be induced by cold air, such as nasal and bronchial hyperresponsiveness.…”

Section: Figmentioning

confidence: 99%

Ventilation System, Indoor Air Quality, and Health Outcomes in Parisian Modern Office Workers

Denis

Annesi

Festy

et al. 1997

Environmental Research

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Section: Figmentioning

confidence: 99%

Ventilation System, Indoor Air Quality, and Health Outcomes in Parisian Modern Office Workers

Denis

Annesi

Festy

et al. 1997

Environmental Research

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“…It has been well documented that indoor air pollution is a risk factor for the development of respiratory symptoms and illnesses in children (Ware et al, 1984;Samet and Lambert, 1991;Forastiere et al, 1992;Venners et al, 2002). In the current literature of air pollution epidemiology, residential gas combustion is often considered to be a major source of indoor air pollution (Dijkstra et al, 1990;Neas et al, 1994;Cuijpers et al, 1995;Pikhart et al, 1999).…”

Section: Introductionmentioning

confidence: 99%

Exposure–response relationships between lifetime exposure to residential coal smoke and respiratory symptoms and illnesses in Chinese children

Qian

Zhang

Korn

et al. 2004

J Expo Sci Environ Epidemiol

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Data collected in a large epidemiologic study were analyzed to examine respiratory health effects of residential coal use in 7058 school children living in the four Chinese cities of Chongqing, Guangzhou, Lanzhou, and Wuhan. A Scenario Evaluation Approach was used to develop two exposure variables, heating coal smoke and cooking coal smoke. Estimated lifetime exposures to heating coal smoke and cooking coal smoke were both classified into fourlevel ordinal scales, as follows: no reported exposure (control); lightly exposed; moderately exposed; and heavily exposed. Zero-one dummy variables were constructed for each exposure level other than the control level (total six variables). These variables were entered into the analytical model. We tested for exposure-response relationships using logistic regression models, while controlling for other relevant covariates, including an indicator variable of ambient air pollution levels. We observed monotonic and positive exposure-response relationships of exposure to heating coal smoke with modeled odds ratios (ORs) of phlegm, cough with phlegm, and bronchitis. Other health outcomes were not associated with such exposure in a monotonic exposureresponse pattern. However, ORs for cough, wheeze, and asthma were all higher in the exposed groups than in the control group. We observed no consistent associations between cooking coal smoke and the examined health outcomes. We conclude that exposure to heating coal smoke could have adverse effects on children's respiratory symptoms and illnesses in these four Chinese cities.

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Human Milk Research for Answering Questions about Human Health

Wang

Bates

Goldstein

et al. 2005

Journal of Toxicology and Environmental Health, Part A

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Concerns regarding human milk in our society are diverse, ranging from the presence of environmental chemicals to the health of breastfed infants and the economic value of breastfeeding to society. The panel convened for the Technical Workshop on Human Milk Surveillance and Biomonitoring for Environmental Chemicals in the United States, held at the Hershey Medical Center, Pennsylvania State College of Medicine, on 24--26 September 2004, considered how human milk research may contribute to environmental health initiatives to benefit society. The panel concluded that infant, maternal, and community health can benefit from studies using human milk biomonitoring. Unlike other biological specimens, human milk provides information regarding exposure of the mother and breastfed infant to environmental chemicals. Some of the health topics relevant to this field of research include disorders of growth and development in infants, cancer origins in women, and characterization of the trend of exposure to environmental chemicals in the community. The research focus will determine the design of the study and the need for the collection of alternative biological specimens and the long-term storage of these specimens. In order to strengthen the ability to interpret study results, it is important to identify reference ranges for the chemicals measured and to control for populations with high environmental chemical exposure, because the amount of data on environmental chemical levels in human milk that is available for comparison is extremely limited. In addition, it will be necessary to validate models used to assess infant exposure from breastfeeding because of the variable nature of current models. Information on differences between individual and population risk estimates for toxicity needs to be effectively communicated to the participant. Human milk research designed to answer questions regarding health will require additional resources to meet these objectives.

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Epidemiologic Approaches for Assessing Health Risks from Complex Mixtures in Indoor Air

Cited by 4 publications

References 12 publications

Ventilation System, Indoor Air Quality, and Health Outcomes in Parisian Modern Office Workers

Ventilation System, Indoor Air Quality, and Health Outcomes in Parisian Modern Office Workers

Exposure–response relationships between lifetime exposure to residential coal smoke and respiratory symptoms and illnesses in Chinese children

Human Milk Research for Answering Questions about Human Health

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