Epidemiologic Study of Pseudomonas aeruginosa in Critical Patients and Reservoirs

Corona-Nakamura, Ana Luisa; Novales, María Guadalupe Miranda; Leaños-Miranda, Blanca; Portillo-Gómez, L; Hernández-Chávez, Abel; Anthor-Rendón, Juan; Aguilar-Benavides, Sergio

doi:10.1016/s0188-4409(01)00267-3

Cited by 43 publications

(26 citation statements)

References 18 publications

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“…We noticed that, among cephalosporin, a high resistance rate was exhibited against cefepime and cefotriaxone, which was consistent with other reports [20,21,30]. In contrast, earlier studies have reported cefepime to be the most effective antimicrobial agent against P. aeruginosa [31,[32][33]. However, this contradiction may be due to the continuous evolution of MDR strains worldwide.…”

Section: Discussionsupporting

confidence: 90%

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

Helal¹,

Khan²

2015

Am. J. Biomed. Sci.

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One of the serious and growing challenges for infection control programs worldwide is hospital acquired infections. Pseudomonas aeruginosa is considered the most common cause of hospital acquired Gramnegative infections. Intensive exposure of hospital pathogens to biocides may result in the emergence of resistance not only to the biocides, but possibly to antibiotics as well. Thus, the current study was done to investigate the prevalence of qacE∆1 and qacE genes and their correlation to antibiotics and biocides resistance in Pseudomonas aeruginosa isolated in Egypt. The antimicrobial activity of six biocides against drug sensitive and multi-drug resistant Pseudomonas aeruginosa was evaluated. Phenol and formalin displayed a higher antimicrobial activity compared to other biocides tested. Minimum inhibitory concentration (MIC) values of chlorine releasing agents were higher than the dilution prescribed by their manufactures. The qacE∆1 gene was identified in 57.8% of multidrug resistant isolates and 21.4% in susceptible strains, While, qacE gene was only detected among multi-drug resistant Pseudomonas aeruginosa. This study reported a correlation between qacE∆1 and multidrug resistance Pseudomonas aeruginosa, while there was no correlation between the presence of qac genes and increased MIC values to biocides. The effectiveness of biocides is very important to control microbial population and prevent the transmission of infections in hospitals. In conclusion we highlight the need for health care facilities to assess the antimicrobial effectiveness of biocides periodically.

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Section: Discussionsupporting

confidence: 90%

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

Helal¹,

Khan²

2015

Am. J. Biomed. Sci.

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“…The prevalence of P.aeruginosa infection in our study 316/2076 (15.22%) were similar to (18.2%) studies of Gad et al, [16]. Resistance to the quinolones was 35-45% (ciprofloxacillin 42%,ofloxacin 39.5%) similar to Corona-Nakamura et al, [17].…”

Section: Discussionsupporting

confidence: 90%

Plasmid Profile Analysis and bla VIM Gene Detection of Metalo β-lactamase (MBL) Producing Pseudomonas aeruginosa Isolates from Clinical Samples

Jayanthi

Jeya

2014

JCDR

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“…Hospital spread of P. aeruginosa strains has been reported, facilitated by the ability of this organism to survive in nosocomial equipment and solutions. 10 Müller-Premru and Gubina 11 found specific genotypes of multidrug-resistant P. aeruginosa in different seasons of the year in a hospital in Slovenia, while CoronaNakamura et al 10 reported clonal dissemination of P. aeruginosa among patients, staff and the hospital environment in a medical centre in Guadalajara city, México. In Brazil, Sader et al 12 reported an imipenem-resistant P. aeruginosa clonal type present in different patients, suggesting horizontal transmission in a hospital in São Paulo.…”

Section: Introductionmentioning

confidence: 99%

Identification of an imipenem-resistant Pseudomonas aeruginosa clone among patients in a hospital in Rio de Janeiro

Kokis

Moreira

Pellegrino

et al. 2005

Journal of Hospital Infection

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Epidemiologic Study of Pseudomonas aeruginosa in Critical Patients and Reservoirs

Cited by 43 publications

References 18 publications

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

QacE and QacE?1 Genes and Their Correlation to Antibiotics and Biocides Resistance Pseudomonas aeruginosa

Plasmid Profile Analysis and bla VIM Gene Detection of Metalo β-lactamase (MBL) Producing Pseudomonas aeruginosa Isolates from Clinical Samples

Identification of an imipenem-resistant Pseudomonas aeruginosa clone among patients in a hospital in Rio de Janeiro

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