Epidemiological and Clinical Characteristics of COVID-19 in Adolescents and Young Adults

Liao, Jiaqiang; Fan, ST; Chen, Jing; Wu, Jianglin; Xu, Shunqing; Guo, Yuming; Li, Chunhui; Zhang, Xianxiang; Wu, Chuansha; Mou, Huaming; Song, Chenxi; Feng, Li; Wu, Guicheng; Zhang, Jingjing; Guo, Li’an; Liu, Huawen; Lv, Jinglong; Xu, Lianyong; Lang, Chunhui

doi:10.1016/j.xinn.2020.04.001

Cited by 117 publications

(102 citation statements)

References 18 publications

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“…Our study's gender ratio was 1:2.4 with male preponderance. Other studies [15,18] showed male preponderance while a study by Satici et al [19] mainly evaluating adaptation of FCV-19S in Turkish population showed female preponderance.…”

Section: Resultsmentioning

confidence: 88%

Covid-19 Demographics from a Tertiary Care Center: Does It Depreciate Quality-of-Life?

Revathishree

Sudarsan

Indu

et al. 2020

Indian J Otolaryngol Head Neck Surg

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Novel Coronavirus-disease-2019 (Covid-19) caused by the severe-acute-respiratory-syndrome coronavirus-2 (SARS-CoV-2) shows a rapid spread all over the world. It's still an ongoing pandemic with greater morbidity and mortality. In our study, we describe clinical features, and demographics of patients presenting to our tertiary care center with Covid-19 infection. Global burden was around 14 million Covid-19 positive cases with .5 million deaths and rising as per WHO update. A descriptive analytical cross-sectional study was carried out from June 1st to 30th, 2020 in a tertiary care center. Patients who tested positive by Reverse Transcriptase-Polymerase chain reaction were included in the study and clinical characteristics and outcome of the patients were analyzed along with impact on quality-of-life. Sample size was 250. Mean age was around 41 years, with age range from 15 to 75 years. Gender ratio was 1:2.4, with male preponderance. Most common presenting symptom was throat pain (60%). Rhinorrhea and sneezing complaints were not recorded. Clinical categorization was done and scored accordingly. Clinical outcomes of above patients showed complication rate 5.2%, mortality rate .8%, with discharge and recovery rate being rate 94.8% and 96% respectively. Fear of COVID-19 scale was used to assess quality-of-life impact. We found throat pain was the most common symptom in our study. No cases reported with rhinorrhea/sneezing. Good recovery rate noted. Quality-of-life impacted.

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Section: Resultsmentioning

confidence: 88%

Covid-19 Demographics from a Tertiary Care Center: Does It Depreciate Quality-of-Life?

Revathishree

Sudarsan

Indu

et al. 2020

Indian J Otolaryngol Head Neck Surg

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“…The searches for studies about asymptomatic or presymptomatic SARS-CoV-2 on 25 March, 20 April, and 10 June resulted in 89, 230, and 688 records for screening (S1 Fig). In the first version of the review [7], 11 articles were eligible for inclusion [17][18][19][20][21][22][23][24][25][26][27], version 2 [8] identified another 26 eligible records , and version 3 identified another 61 eligible records . After excluding four articles for which more recent data became available in a subsequent version [25,29,30,35], the total number of articles included was 94 (S1 Table) [17][18][19][20][21][22][23][24][26][27][28][31][32][33][34].…”

Section: Resultsmentioning

confidence: 99%

“…The first three strata in Fig 1 involve studies that reported on different types of contact investigation, which start with an identified COVID-19 case. The studies reporting on singlefamily clusters (21 estimates from 16 studies in China, n = 102 people with SARS-CoV-2) all included at least one asymptomatic person [17,18,[21][22][23]26,44,49,50,70,[73][74][75][76]85,110]. The summary estimate was 34% (95% CI 26%-44%, prediction interval 25%-45%).…”

Section: Proportion Of People With Asymptomatic Sars-cov-2 Infectionmentioning

confidence: 99%

Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: A living systematic review and meta-analysis

et al. 2020

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Background There is disagreement about the level of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We conducted a living systematic review and metaanalysis to address three questions: (1) Amongst people who become infected with SARS-CoV-2, what proportion does not experience symptoms at all during their infection? (2) Amongst people with SARS-CoV-2 infection who are asymptomatic when diagnosed, what proportion will develop symptoms later? (3) What proportion of SARS-CoV-2 transmission is accounted for by people who are either asymptomatic throughout infection or presymptomatic? Methods and findings We searched PubMed, Embase, bioRxiv, and medRxiv using a database of SARS-CoV-2 literature that is updated daily, on 25 March 2020, 20 April 2020, and 10 June 2020. Studies of people with SARS-CoV-2 diagnosed by reverse transcriptase PCR (RT-PCR) that documented follow-up and symptom status at the beginning and end of follow-up or modelling studies were included. One reviewer extracted data and a second verified the extraction, with disagreement resolved by discussion or a third reviewer. Risk of bias in empirical studies was assessed with an adapted checklist for case series, and the relevance and credibility of modelling studies were assessed using a published checklist. We included a total of 94 studies. The overall estimate of the proportion of people who become infected with SARS-CoV-2 and remain asymptomatic throughout infection was 20% (95% confidence interval [CI] 17-25) with a prediction interval of 3%-67% in 79 studies that addressed this review question. There was some evidence that biases in the selection of participants influence the estimate. In seven studies of defined populations screened for SARS-CoV-2 and then

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“…However, this was not assessed in the study. Given the relatively young age of participants in this study, if infected with COVID-19, they may have had less severe symptoms, or no symptoms at all, 30 and thus may also explain why they never got tested. Moreover, young adults have been shown to be less likely to social distance, as supported by this study where most participants did not self-quarantine after protesting, possible because they overrate their own control over whether they get sick or they take social cues from peers.…”

Section: Discussionmentioning

confidence: 99%

"I felt what was happening in our country [USA] with race was so much scarier than the [COVID-19] virus." Black Lives Matter protesters’ beliefs and practices during the COVID-19 pandemic

Arana-Chicas

Jones

Cartujano-Barrera

et al. 2020

Preprint

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Background: The killing of George Floyd triggered the Black Lives Matter protests against police brutality and social injustices in the midst of the COVID-19 pandemic. No research to date has assessed the COVID-19 prevention practices and beliefs of protesters. The purpose of this study was to assess COVID-19 prevention practices and beliefs of Black Lives Matter protesters in the USA. Methods: A pilot mixed methods study was employed. Participants completed a survey collecting data on their frequency in following COVID-19 recommended guidelines and answered open-ended interview questions to elucidate the results from the survey. Results: Twenty participants completed the study. Participants’ average age was 29 and most participants were female (80%) and black (75%). Most always or almost always properly wore their masks (50% and 25%, respectively) and washed their hands during a protest 2-3 times or more than 3 times (35% and 50%, respectively). Although all believed that COVID-19 testing is important (90%), most had never been tested (85%) and most did not self-quarantine for 14 days after protesting (95%). Moreover, most participants reported never or rarely following social distancing guidelines at a protest (25% and 30%, respectively) and most reported being Not at all or Slightly concerned about COVID-19 while at a protest (25% and 30%, respectively). Qualitative data highlighted the following themes: 1) Fighting for social justice, 2) Protesting being more important than COVID-19, 3) Unable to keep 6 ft distance, 4) Masks worn most of the time, 5) Protests sparked global movement, and 6) Increasing awareness of injustices. Conclusion: Although protesters believe that both the fight for social justice and taking precautions during the COVID-19 pandemic are important, they believe the fight for social justice is more important than the COVID-19 pandemic. However, they understand the importance of COVID-19 and try to practice the recommended guidelines to prevent its spread while protesting. These results make an important contribution for policies for controlling the spread of the disease, and also understanding human behavior of protesting for social justice during a pandemic.

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Epidemiological and Clinical Characteristics of COVID-19 in Adolescents and Young Adults

Cited by 117 publications

References 18 publications

Covid-19 Demographics from a Tertiary Care Center: Does It Depreciate Quality-of-Life?

Covid-19 Demographics from a Tertiary Care Center: Does It Depreciate Quality-of-Life?

Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: A living systematic review and meta-analysis

"I felt what was happening in our country [USA] with race was so much scarier than the [COVID-19] virus." Black Lives Matter protesters’ beliefs and practices during the COVID-19 pandemic

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