Epidemiological, clinical, microbiological and therapeutic differences in tuberculosis disease in patients with and without HIV infection

Martínez‐Sanz, Javier; Lago-Gómez, María Rosa; Rodríguez-Zurita, María Elena; Martín-Echevarría, Esteban; Torralba, Miguel

doi:10.1016/j.medcle.2018.02.012

Cited by 3 publications

(1 citation statement)

References 8 publications

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“…Наличие у ВИЧ-инфицированных сочетанной инфекционной и неинфекционной патологии, способной вызывать симптомы, сходные с клинической картиной туберкулеза, требует проведения обязательной дифференциальной диагностики туберкулеза. Многие оппортунистические заболевания у пациентов с ВИЧ-инфекцией имеют сходную с туберкулезом симптоматику, включая микобактериоз, пневмоцистоз, цитомегаловирусную (CMV), герпесвирусные инфекции и другие бактериальные/грибковые, лимфопролиферативные заболевания и септические состояния [6][7][8][9][10][11]. От оперативности выполнения и качества диагностических мероприятий, своевременного перевода пациента в профильное лечебное учреждение и раннего начала этиотропной терапии туберкулеза напрямую зависит исход заболевания.…”

Section: диагностическое значение выявления Lam-антигена микобактерии...unclassified

Diagnostic value of detection of LAM-antigen of mycobacteria tuberculosis in the urine of patients with HIV infection

Dobronravova¹,

Maksimov²,

Martynova³

et al. 2022

Infectious diseases: News, Opinions, Training

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Журнал для непрерывного медицинского образования врачей ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ микобактериоз), что составило 58,1%. У всех пациентов с неподтвержденным диагнозом туберкулеза или микобактериоза результат TB-LAM-теста был отрицательным. Среди 18 пациентов с положительным результатом TB-LAM-теста 17 (94,4%) был выставлен заключительный диагноз туберкулеза или микобактериоза: туберкулез -15 (88,2%), микобактериоз -2 (11,8%). 1 пациент выбыл из исследования (окончательный диагноз неизвестен, не состоит на диспансерном учете).Заключение. У 18 ВИЧ-инфицированных пациентов с положительным результатом TB-LAM-теста в утренней порции мочи в 99,4% случаев был выставлен заключительный диагноз туберкулеза или микобактериоза. TB-LAM-тест -быстрый, специфичный и простой в исполнении метод исследования для выявления микобактериальной инфекции у ВИЧ-инфицированных пациентов на стадии иммунодефицита.Финансирование. Исследование не имело спонсорской поддержки Конфликт интересов. Авторы заявляют об отсутствии конфликта интересов.

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Section: диагностическое значение выявления Lam-антигена микобактерии...unclassified

Diagnostic value of detection of LAM-antigen of mycobacteria tuberculosis in the urine of patients with HIV infection

Dobronravova¹,

Maksimov²,

Martynova³

et al. 2022

Infectious diseases: News, Opinions, Training

View full text Add to dashboard Cite

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Morbidity Trends and Risk of Tuberculosis: Mexico 2007–2017

Bello–López

León-García

Rojas-Bernabé

et al. 2019

Canadian Respiratory Journal

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Background. To know the current status of the epidemiological and geographic distribution of tuberculosis and its complication meningeal tuberculosis in Mexico, this work analyzes national surveillance data (ten years) issued by the General Directorate of Epidemiology (GDE). Methods. An observational and retrospective analysis of monthly and annual reports of pulmonary and meningeal tuberculosis cases from January 2007 to December 2017 was performed on the annual reports issued by the GDE in Mexico. The number of cases and incidence were classified by year, state, age group, gender, and seasons. Results. A national case distribution map of pulmonary and meningeal tuberculosis incidence was generated. During this period, a total of 184,003 and 3,388 cases were reported with a median of 16,727.5 and 308 cases per year for pulmonary and meningeal tuberculosis diseases, respectively. The number of cases and incidence of pulmonary and meningeal tuberculosis per year showed that male gender presented a continuous increase in both parameters. The geographic analysis of the distribution of cases of tuberculosis showed that states like Guerrero, Tabasco, and Veracruz presented higher means of tuberculosis cases during this period. Northern states had the highest number of cases in the country compared to other states. In Mexico, pulmonary tuberculosis and meningeal tuberculosis are seasonal. Interestingly, cases of meningeal tuberculosis show an increase during October and November (autumn). Conclusions. In Mexico, during the years 2007–2017, there has been an increase in the proportion of male TB patients. It remains necessary to implement strategies to detect TB in the adult population, especially among men, because tuberculosis could be difficult to recognize in an early stage in the population, and the appearance of resistant strains can cause an increase in the incidence of the disease.

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Factors affecting the TB screening indicators in people living with HIV in the regions of Northwestern Federal District of the Russian Federation

Загдын

Verbitskaya

Соколович

et al. 2021

VIČ-infekc. immunosupr.

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The aim of the study is to know the tuberculosis screening measures and factors affecting their effectiveness among people living with HIV in the Northwestern District of the Russian Federation. In the study the data obtained from federal statistical surveys on HIV and tuberculosis during 2007–2018 have been used. In several regions of the Northwestern District there is a significant decrease in the results of the screening measures (p<0,05): in Kaliningrad, Leningrad, Pskov regions and Karelia Republic, which is associated with the density of cumulation of patients with advanced stages of HIV-infection (s=0,81, p<0,001) and with the share of subjects tested positively for HIV, but not registered at the AIDS Centers in the year of obtaining the positive results. In the regional TB/HIV programs it is necessary to take into account the level of cumulation of HIV cases on advanced stages in the region and the resources should be directed towards the tuberculosis screening among the patients who are on advanced HIV stages.

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Epidemiological, clinical, microbiological and therapeutic differences in tuberculosis disease in patients with and without HIV infection

Cited by 3 publications

References 8 publications

Diagnostic value of detection of LAM-antigen of mycobacteria tuberculosis in the urine of patients with HIV infection

Diagnostic value of detection of LAM-antigen of mycobacteria tuberculosis in the urine of patients with HIV infection

Morbidity Trends and Risk of Tuberculosis: Mexico 2007–2017

Factors affecting the TB screening indicators in people living with HIV in the regions of Northwestern Federal District of the Russian Federation

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