Epidemiological study, clinical spectrum and associations of childhood vitiligo in a tertiary care centre

Rangaraj, Murugaiyan

doi:10.18203/issn.2455-4529.intjresdermatol20163976

Cited by 3 publications

(4 citation statements)

References 7 publications

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“…This is similar to studies by Rangaraj, Keyur et al, and Lahlou. 5,7,8 Positive family history was seen in 15% of cases in this study. Manali et al and Rangaraj have recorded a positive family history in 17.14% and 12.5% of cases respectively.…”

Section: Resultssupporting

confidence: 48%

“…This is similar to studies by Manali et al, Puri, Rangaraj. [3][4][5] The most common age group involved was 5 to 9 years. Manali et al and Beliappa et al have noted maximum number of cases in 6-9 years and 7-12 years age groups respectively.…”

Section: Resultsmentioning

confidence: 99%

“…Manali et al and Rangaraj have recorded a positive family history in 17.14% and 12.5% of cases respectively. 3,5 Leukotrichia was seen in 25% of cases. Similar findings were noted by Puri and Keyur et al 4,7 A positive koebners phenomenon was seen in 20% of cases.…”

Section: Resultsmentioning

confidence: 99%

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Clinical profile of childhood vitiligo at a tertiary hospital in North Kerala

Kambil

2018

Int J Res Dermatol

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Background: Vitiligo is an autoimmune disorder characterised by depigmentation of skin and/or mucosa. It is seen in adults as well as children and affects both males and females.Methods: 40 children under 14years of age with clinically diagnosed vitiligo were included in this study. The study was conducted in the dermatology outpatient department from March 2017 to February 2018. The various clinical and epidemiological features observed in the patients are described.Results: The most common age group affected was 5 to 9 years (45%). Vitiligo was more common in girls (55%) and vitiligo vulgaris was the most common clinical type (35%). Extremities were the most common site of onset of the disease (37.5%). Leukotrichia, Koebners phenomenon and a positive family history were seen in a significant number of cases.Conclusions: Vitiligo is common in children and is associated with significant psychological trauma leading to poor quality of life. Updated knowledge about the various clinical patterns will help in early correct diagnosis and proper treatment.

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Section: Resultssupporting

confidence: 48%

Section: Resultsmentioning

confidence: 99%

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Clinical profile of childhood vitiligo at a tertiary hospital in North Kerala

Kambil

2018

Int J Res Dermatol

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“…17 We encountered maximum cases between the age group of 6 to 10 years with 40%, whereas it was 45.5% in the study by Afsar FS et al 15 In our study, a family history of vitiligo was seen in 14% of cases. It is similar to Indian studies by Hafi et al 18 12%, Murugaiyan et al 19 12.5%, PK Sheth et al 20 14% and SM Kambil et al 21 15%, but much lesser than the findings of Nicolaidou et al 22 35% respectively. Positive familial incidence indicate that genetic influences have a role in the pathogenesis of vitiligo.…”

Section: Discussionsupporting

confidence: 89%

Evaluation of thyroid abnormalities in childhood vitiligo from a tertiary care centre: A case-control study

Salecha¹,

Sridevi³

et al. 2023

PJMS

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Vitiligo is an usual acquired pigmentary disorder of the skin characterized by well-circumscribed depigmented macules and patches. Though the association between vitiligo and thyroid disorders has been suggested, only a few studies from India and overseas have paid attention to describe the association between vitiligo and thyroid abnormalities, particularly in children. Hence, this study was taken up for evaluating thyroid disease in childhood vitiligo compared to controls in a tertiary care centre.This was a hospital-based case-control study conducted at a tertiary teaching hospital over 18 months which included 50 new patients of vitiligo and 50 age and sex-matched controls. Blood samples were garnered from cases and controls to access the levels of free triiodothyronine (fT3), free thyroxine (fT4), Thyroid-stimulating hormone ( TSH), anti-thyroid peroxidase (anti-TPO), and anti-thyroglobulin (anti –Tg).In our study, females outnumbered males in both groups. The frequencies of thyroid function and thyroid autoantibody abnormalities among vitiligo patients and control were 32% and 6%, respectively. The difference between case and controls for thyroid function abnormality was significant with a p-value of 0.001.Our study found a significant association betwixt thyroid disease and childhood vitiligo. Thus, evaluating vitiligo patients for thyroid abnormalities help to detect thyroid diseases or determine the possibility of eventual onset.

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Clinico epidemiological study of vitiligo in children

Ali¹,

Basha²

2020

IJCED

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Vitiligo is a common acquired pigmentary disorder characterized by well defined hypopigmented or depigmented macules due to absence or decrease in melanocytes. To study the clinico epidemiological pattern of vitiligo in children. A group of 50 consecutive children attending out patient in the department of DVL at Shadan Institute of Medical Sciences will be included. All the patients meeting the inclusion criteria were taken into the study. A designed, coded proforma was used for recording all the findings. Almost half of the children taken for study belongs to age group of 9-11 years. Majority of the study population were females. The most common pattern of vitiligo was vitiligo vulgaris. Common site of involvement was lower limbs. The most common associated feature was leukotrichia. The most common associated condition was photosensitivity. Family history was positive in only 4% of cases. Most of them were in the active stage of disease. The female predominance was high in prevalence of vitiligo in children and an earlier age of onset seen among children with family history of vitiligo or autoimmune disorders. Vitiligo vulgaris is the most common presentation, and lower limbs being the most common site of involvement in children

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Epidemiological study, clinical spectrum and associations of childhood vitiligo in a tertiary care centre

Cited by 3 publications

References 7 publications

Clinical profile of childhood vitiligo at a tertiary hospital in North Kerala

Clinical profile of childhood vitiligo at a tertiary hospital in North Kerala

Evaluation of thyroid abnormalities in childhood vitiligo from a tertiary care centre: A case-control study

Clinico epidemiological study of vitiligo in children

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