Epidemiological study of malignant tumors in the oral and maxillofacial region: survey of member institutions of the Japanese Society of Oral and Maxillofacial Surgeons, 2002

Ariyoshi, Yasunori; Shimahara, Masashi; Omura, Ken; Yamamoto, Etsuhide; Mizuki, Harumi; Chiba, Hiroshige; Imai, Yutaka; Fujita, Shigeyuki; Shinohara, Masanori; Seto, Kanichi

doi:10.1007/s10147-007-0756-9

Cited by 47 publications

(48 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is twice more common in man than in woman. 17,18,19 The predominate site of intraoral melanoma is the hard plate accounting for two thirds of all oral melanomas. Other sites include the maxillary alveolus, mandible, tongue and buccal mucosa.…”

Section: Oral Mucosal Melanomamentioning

confidence: 99%

Dermoscopy of pigmented oral lesions

Olszewska

Banka²,

Górska³

et al. 2008

J Dermatol Case Rep

View full text Add to dashboard Cite

Dermoscopy is a noninvasive diagnostic technique that permits the visualization of morphologic features that are not visible to the naked eye. It is currently widely used for examination of pigmented skin lesions and early detection of cutaneous melanoma. Dermoscopy of mucous membranes is significantly less investigated and less popular among clinicians.This article reviews current knowledge about characteristic dermoscopy features of pigmented lesions of the oral mucous membranes and lips. It has to emphasized that a major advantage of dermoscopy is the capability to exclude melanoma and avoid unnecessary excisional biopsies and extensive surgery, often resulting in significant disfigurement of face and oral cavity.It has to be pointed out that there is a necessity to intensify research, which would result in clear-cut dermoscopy criteria for mucosal melanoma and the need for constructing thin, flexible dermoscopes suitable for investigation of oral mucous membranes. Dermoscopy is a noninvasive diagnostic technique that permits the visualization of morphologic features that are not visible to the naked eye. It is currently widely used for examination of pigmented skin lesions and early detection of cutaneous melanoma. 1,2 Despite increasing popularity in examination of skin lesion, the methods remains unpopular in investigating pigmented lesions oral mucous membranes and lips. Dermoscopy of pigmented oral lesionsPigmented mucosal lesions represent a group of rare entities differing in etiopathogenesis, histology, dermoscopy and clinical course. Solitary pigmented lesions of melanocytic origin are uncommon in the oral mucosa. These lesions include the oral and labial melanotic macules, oral melanocytic nevi, oral melanoacanthomas and oral melanomas. 3 As shown by Buchner et al 4 oral and labial melanotic macules are the most common melanocytic lesions. The relative frequency of oral melanoma accounts for 0.6% of the entire melanocytic group of oral pigmented lesions (Table 1). Despite low frequency, early detection of melanoma is the main aim of dermoscopic examinations of the oral mucous membranes and the lip. An additional benefit of dermoscopy is exclusion of melanoma of the oral mucous membranes or the lip in doubtful cases, what may save patients the discomfort of extensive and unnecessary surgery.In this paper, we review current knowledge about dermoscopy of pigmented lesions localized on the mucous membranes of the oral cavity and the semi-mucosa of lips. Table 1 Relative frequency of oral solitary melanocytic lesions. 4

show abstract

Section: Oral Mucosal Melanomamentioning

confidence: 99%

Dermoscopy of pigmented oral lesions

Olszewska

Banka²,

Górska³

et al. 2008

J Dermatol Case Rep

View full text Add to dashboard Cite

show abstract

“…However, while most of the cases of OC occur between 50 and 70 years of age (Bhurgri et al, 2006), it still could occur in children as early as 10 years of age in the absence of any known risk factors (Khan and Naushad, 2011;Solanki et al, 2012). With advancing age, the number of people affected by OC increase (Ariyoshi et al, 2008). The mean age of occurrence of cancer in different parts of oral cavity is usually between 51-55 years in most of the countries but higher around 64 years, in Thailand (Bhurgri et al, 2006).…”

Section: Age and Gendermentioning

confidence: 99%

“…The majority (84-97%) of OCs are SCCs (Bhurgri et al, 2003;Sawair et al, 2007;Ariyoshi et al, 2008;Kruaysawat et al, 2010) which arise from pre-existing "potentially malignant" lesions or more often from normal appearing epithelium. OC spreads locally involving perioral structures and metastasises to local regional lymph nodes.…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of Oral Cancer in Asia in the Past Decade- An Update (2000-2012)

Rao¹,

Mejía²,

Roberts‐Thomson³

et al. 2013

Asian Pacific Journal of Cancer Prevention

407

256

View full text Add to dashboard Cite

The prevalence of oral cancers (OC) is high in Asian countries, especially in South and Southeast Asia. Asian distinct cultural practices such as betel-quid chewing, and varying patterns of tobacco and alcohol use are important risk factors that predispose to cancer of the oral cavity. The aim of this review is to provide an update on epidemiology of OC between 2000 and 2012. A literature search for this review was conducted on Medline for articles on OC from Asian countries. Some of the articles were also hand searched using Google. High incidence rates were reported from developing nations like India, Pakistan, Bangladesh, Taiwan and Sri Lanka. While an increasing trend has been observed in Pakistan, Taiwan and Thailand, a decreasing trend is seen in Philippines and Sri Lanka. The mean age of occurrence of cancer in different parts of oral cavity is usually between 51-55 years in most countries. The tongue is the leading site among oral cancers in India. The next most common sites in Asian countries include the buccal mucosa and gingiva. The 5 year survival rate has been low for OC, despite improvements in diagnosis and treatment. Tobacco chewing, smoking and alcohol are the main reasons for the increasing incidence rates. Low socioeconomic status and diet low in nutritional value lacking vegetables and fruits contribute towards the risk. In addition, viral infections, such as HPV and poor oral hygiene, are other important risk factors. Hence, it is important to control OC by screening for early diagnosis and controlling tobacco and alcohol use. It is also necessary to have cancer surveillance at the national-level to collect and utilise data for cancer prevention and control programs.

show abstract

“…Squamous cell carcinoma developing from the oral cavity is a common malignant neoplasm of the head and neck, with tongue carcinomas accounting for 25-40% of all oral carcinomas (1,2). Over 50% of patients experience a relapse and the incidence is expected to increase in the next few decades (3).…”

Section: Introductionmentioning

confidence: 99%

Differential expression of fatty acid-binding proteins and pathological implications in the progression of tongue carcinoma

Ohyama

Kawamoto

Chiba

et al. 2013

Molecular and Clinical Oncology

View full text Add to dashboard Cite

Abstract. Tongue carcinomas are common malignancies of the oral cavity. Understanding the molecular mechanisms behind the disease progression is a prerequisite for improving patient prognosis. Fatty acid-binding proteins (FABPs) are cytoplasmic lipid chaperones that affect cellular organization and energy production. Although their aberrant expression is involved in carcinoma progression, its role in the pathology of tongue carcinomas remains unclear. In the present study, the immunohistochemical expression of FABP4 and FABP5 in tongue carcinomas (n=58) and its involvement in the clinicopathological parameters were examined. Normal tongue epithelial cells expressed FABP5, an epidermal-type FABP, but not FABP4, an adipocyte-type FABP. The cytoplasmic staining of FABP5 was increased in carcinomas with advanced T-stage (P<0.05) and clinical stage (P<0.05). Ectopic expression of FABP4 was detected in almost all carcinomas, although its role in disease progression remains undetermined. Upregulation of FABP5 in the wounded skin of genetically normal mice indicated that microenvironmental tissue factors induce FABP5 expression. The results of the present study demonstrated the aberrant expression of FABP4 and FABP5 in tongue carcinomas and suggested the involvement of FABP5 in disease progression.

show abstract

Epidemiological study of malignant tumors in the oral and maxillofacial region: survey of member institutions of the Japanese Society of Oral and Maxillofacial Surgeons, 2002

Cited by 47 publications

References 17 publications

Dermoscopy of pigmented oral lesions

Dermoscopy of pigmented oral lesions

Epidemiology of Oral Cancer in Asia in the Past Decade- An Update (2000-2012)

Differential expression of fatty acid-binding proteins and pathological implications in the progression of tongue carcinoma

Contact Info

Product

Resources

About