Epidemiology and antimicrobial susceptibility profiles of pathogens causing urinary tract infections in the Asia-Pacific region: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2010–2013

Jean, Shio Shin; Coombs, Geoffrey W.; Ling, T. K. W.; Balaji, V.; Rodrigues, Camilla; Mikamo, Hiroshige; Kim, Jong Hun; Rajasekaram, Datin Ganeswrie; Mendoza, Myrna; Tan, Thean Yen; Kiratisin, Pattarachai; Ni, Yizhao; Barry, Weinman; Xu, Yingchun; Hsueh, Po-Ren

doi:10.1016/j.ijantimicag.2016.01.008

Cited by 115 publications

(93 citation statements)

References 15 publications

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“…The common occurrence and resistance to ESBL‐positive uropathogens in patients with urinary stones should not be ignored. The resistance of ESBL‐positive uropathogens to antimicrobial agents was significantly higher than that of ESBL‐negative uropathogens, similar to the previous study . Carbapenems, amikacin, cefotetan, piperacillin/tazobactam and tigecycline were effective to ESBL‐positive uropathogens (resistance <20%).…”

Section: Discussionsupporting

confidence: 87%

The analysis of microbial spectrum and antibiotic resistance of uropathogens isolated from patients with urinary stones

et al. 2018

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Section: Discussionsupporting

confidence: 87%

The analysis of microbial spectrum and antibiotic resistance of uropathogens isolated from patients with urinary stones

et al. 2018

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“…We found a trend that more Gram-positive bacteria (29). They also showed the highest ESBL-producing rate of E. coli was 59.9 in China, and that of K. pneumoniae was 61.3 in the Philippines.…”

Section: Discussionmentioning

confidence: 62%

International Comparison of Causative Bacteria and Antimicrobial Susceptibilities of Urinary Tract Infections between Kobe, Japan, and Surabaya, Indonesia

Kitagawa¹,

Shigemura

Yamamichi

et al. 2018

Jpn J Infect Dis

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SUMMARY:Variation by country in urinary tract infection (UTI)-causative bacteria is partly due to the differences in the use of antibiotics. We compared their frequencies and antibiotic susceptibilities in the treatment of patients with UTI from 2 cities, Kobe, Japan, and Surabaya, Indonesia. We retrospectively analyzed 1,804 urine samples collected from patients with UTI in 2014 (1,251 collected in 11 months at Kobe University Hospital in Kobe and 544 collected in 2 months at Dr. Soetomo Hospital in Surabaya). Surabaya data were divided into adult and pediatric patients because a substantial number of specimens from pediatric-patients had been collected. The results indicated that Escherichia coli was the most common uropathogen (24.1 in Kobe and 39.3 in Surabaya) and was significantly resistant to ampicillin and substantially to first-and third-generation cephalosporins in Surabaya adults but not in Kobe adults (p ＜ 0.01). Enterococcus faecalis was often isolated in Kobe (14.0 ), but not in Surabaya (5.3 ). Klebsiella spp. were isolated at a higher rate in Surabaya pediatric patients (20.3 ) than in Surabaya adults (13.6 ) and Kobe adults (6.6 ). The antibiotic susceptibilities of the isolates form Surabaya isolates tended to be lower than the ones from Kobe. Extended-spectrum β-lactamaseproducing Gram-negative bacteria were detected at a significantly higher rate in Surabaya than in Kobe (p ＜ 0.001). These results showed that the antimicrobial resistance patterns of UTI-causative bacteria are highly variable among 2 countries, and the continuous surveillance of trends in antibiotic resistance patterns of uropathogens is necessary for the future revision of antibiotic use.

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“…Since their description in the 1980s, extended-spectrum β-lactamase (ESBL)-producing organisms have been recognized as a global threat [1][2][3][4]. Through the years, these enzymes have undergone substantial biochemical alterations resulting in the ability to more efficiently hydrolyze β-lactam antibiotics [5].…”

mentioning

confidence: 99%

The Use of Noncarbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase Infections

Tamma¹,

Rodríguez‐Baño

2017

Clinical Infectious Diseases

154

117

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The continued rise in infections caused by extended-spectrum β-lactamase (ESBL)-producing pathogens is recognized globally as one of the most pressing concerns facing the healthcare community. Carbapenems are widely regarded as the antibiotics of choice for the treatment of ESBL-producing infections, even when in vitro activity to other β-lactams has been demonstrated. However, indiscriminant carbapenem use is not without consequence, and carbapenem overuse has contributed to the emergence of carbapenem-resistant Enterobacteriaceae. The use of non-carbapenem β-lactams for the treatment of ESBL infections has yielded conflicting results. In this review, we discuss the available data for the use of cephamycins, cefepime, piperacillin-tazobactam, ceftolozane-tazobactam, and ceftazidime-avibactam for the treatment of ESBL infections.

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Epidemiology and antimicrobial susceptibility profiles of pathogens causing urinary tract infections in the Asia-Pacific region: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART), 2010–2013

Cited by 115 publications

References 15 publications

The analysis of microbial spectrum and antibiotic resistance of uropathogens isolated from patients with urinary stones

The analysis of microbial spectrum and antibiotic resistance of uropathogens isolated from patients with urinary stones

International Comparison of Causative Bacteria and Antimicrobial Susceptibilities of Urinary Tract Infections between Kobe, Japan, and Surabaya, Indonesia

The Use of Noncarbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase Infections

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