Epidemiology and Burden of Diabetic Foot Ulcer and Peripheral Arterial Disease in Korea

Chun, Dong-Il; Kim, Sangyoung; Kim, Jahyung; Yang, Hyeon Jong; Cho, Jae-ho; Yi, Young; Kim, Woo Jong; Won, Sung Hun

doi:10.3390/jcm8050748

Cited by 42 publications

(36 citation statements)

References 21 publications

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“…We agreed with the conclusions and views that information about the epidemiology of amputation and PAD associated with DFU were likely to be crucial for predicting future disease progression and establishing a health-care budget. 21 During the seven years analyzed, all hospital admissions of patients with DFU were recorded, with a mean of 18.1 days (SD 13.55) per case attended. In a Europe-wide study, the corresponding rate has been estimated at 23 days.…”

Section: Discussionmentioning

confidence: 99%

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Cost of Diabetic Foot Ulcer Management in China: A 7-Year Single-Center Retrospective Review

Qu¹,

Wang²,

Wei³

et al. 2020

DMSO

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Background The cost of care for diabetic foot ulcers has became a global economic burden. The study aimed to analyze diabetic foot ulcer cost changes over time and to identify factors associated with these variables, so as to strengthen and improve the management of diabetic foot ulcers. Methods We retrospectively analyzed the data in the electronic medical record system of our wound treatment center. The homepage of the system was queried using the national clinical version 2.0 disease diagnosis code (ICD-10), the data of patient’s basic information were exported. Through the statistics and analysis of these data, the socioeconomic changes and possible risk factors of diabetic foot ulcers management in recent years were obtained. Results There were 3654 patients included in the study, an average of 522 per year. The total cost per patient increased from ¥15,535.58 in 2014 to ¥42,040.60 in 2020, with an average of ¥21,826.91. The average length of stay between 14.29 days and 31.4 days from 2014 to 2020, with an average of 18.10 days. Besides, the average incidence of peripheral arterial disease in diabetic foot ulcers patients admitted was as high as 81.9%, and the average amputation rate was 9.9%. The study reflected the total cost and length of stay of diabetic foot patients increased significantly from 2014 to 2020, which were related to age (>85 years), gender (male), peripheral arterial disease, amputation (P < 0.05). Conclusion A heavy cost from diabetic foot ulcers and its complications was significantly increased yearly, which was related to older age, co-morbidity, amputation and duration of hospitalization. The prevention and treatment of diabetic foot ulcers have a long way to go, early comprehensive prevention and multi-disciplinary cooperation may still be an effective way.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Cost of Diabetic Foot Ulcer Management in China: A 7-Year Single-Center Retrospective Review

Qu¹,

Wang²,

Wei³

et al. 2020

DMSO

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“…9 However, none of the above complications are more devastating than those involving the foot and the incidence of diabetic foot complications are increasing often due to negligence by both patients and physicians. [10][11][12][13] Diabetic foot ulcer has significant health and socioeconomic problems holding adverse effects on the quality of life of the patients and imposing a heavy economic burden on the patient and their family. 14 Diabetic foot problems account for more hospital admission than any other long term complications of diabetes and are responsible for nearly 50% of all-diabetes-related hospital bed days.…”

Section: Introductionmentioning

confidence: 99%

Incidence of Diabetic Foot Ulcer and Its Predictors Among Diabetes Mellitus Patients at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia: A Retrospective Follow-Up Study

Adem¹,

Andargie²,

Teshale³

et al. 2020

DMSO

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The incidence of a diabetic foot ulcer (DFU) is increasing over the previous decade with an increasing prevalence of diabetes mellitus (DM). Despite the increasing incidence of DFU, there is limited information about the problem in Ethiopia. Hence, this study aimed to investigate the incidence of DFU and its predictors among newly diagnosed DM patients who were on follow-up at Felege Hiwot Referral Hospital. Methods: Institution-based retrospective follow-up study was conducted at Felege Hiwot Referral Hospital among newly diagnosed DM patients from January 1, 2009, to December 31, 2018. A simple random sampling method was used to select 401 study participants from a total of 723 eligible population. Data was entered using Epi-Data version 3.1 and exported to STATA version 14 for analysis. The incidence rate was estimated using person-years of observation and Nelson-Aalen cumulative hazard function, showing the cumulative probability of diabetic foot ulcer, was done. The best model (Gompertz) was selected using the AIC and log-likelihood method. Hazard ratio (HR) with its 95% confidence interval was computed and variables having a p-value less than 0.05 in the multivariable model were considered to be significantly associated with DFU. Results: A total of 387 patients were followed retrospectively for a median follow-up time of 95 months. Out of all, 66 (17.05%) patients developed DFU with an incidence rate of 4 cases per 100 person-years of observation. Diabetic nephropathy (adjusted hazard ratio (AHR) = 2.37, 95% CI: 1.33-54.24), diabetic retinopathy (AHR = 5.56, 95% CI: 2.64-11.74), and increased body mass index (AHR = 1.13, 95% CI: 1.01-1.27) were found to increase the hazard of DFU. Conclusion: The incidence of DFU was relatively high. Diabetic nephropathy, diabetic retinopathy, and body mass index were its significant predictors. Therefore, close monitoring of patients with co-morbidities and increased body mass index should be considered to reduce DFU.

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“…The global prevalence rate of DFU has been estimated to be around 6.3% and Asia recorded around 5.5%. There is a high possibility for amputation within the first year of infection, which is around 34.1% with a mortality rate of 5.5% [ 5 ]. Figure 1 shows the condition of DFU.…”

Section: Introductionmentioning

confidence: 99%

Cellulose/Collagen Dressings for Diabetic Foot Ulcer: A Review

Naomi

2020

Pharmaceutics

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Diabetic foot ulcer (DFU) is currently a global concern and it requires urgent attention, as the cost allocation by the government for DFU increases every year. This review was performed to provide scientific evidence on the advanced biomaterials that can be utilised as a first-line treatment for DFU patients. Cellulose/collagen dressings have a biological property on non-healing wounds, such as DFU. This review aims to analyse scientific-based evidence of cellulose/collagen dressing for DFU. It has been proven that the healing rate of cellulose/collagen dressing for DFU patients demonstrated a significant improvement in wound closure as compared to current standard or conventional dressings. It has been scientifically proven that cellulose/collagen dressing provides a positive effect on non-healing DFU. There is a high tendency for cellulose/collagen dressing to be used, as it highly promotes angiogenesis with a rapid re-epithelisation rate that has been proven effective in clinical trials.

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Epidemiology and Burden of Diabetic Foot Ulcer and Peripheral Arterial Disease in Korea

Cited by 42 publications

References 21 publications

<p>Cost of Diabetic Foot Ulcer Management in China: A 7-Year Single-Center Retrospective Review</p>

<p>Cost of Diabetic Foot Ulcer Management in China: A 7-Year Single-Center Retrospective Review</p>

<p>Incidence of Diabetic Foot Ulcer and Its Predictors Among Diabetes Mellitus Patients at Felege Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia: A Retrospective Follow-Up Study</p>

Cellulose/Collagen Dressings for Diabetic Foot Ulcer: A Review

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