Epidemiology and demographics of juvenile idiopathic arthritis in Africa and Middle East

Al‐Mayouf, Sulaiman M.; Mutairi, Muna Al; Bouayed, K.; Habjoka, Sara; Hadef, Djohra; Lotfy, Hayam M.; Scott, Cristiaan; Sharif, Elsadeg; Tahoun, Nouran

doi:10.1186/s12969-021-00650-x

Cited by 26 publications

(19 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The latest review of epidemiological literature of JIA in the Middle Eastern region by Al-Mayouf et al highlights that there is not enough literature describing JIA in this region. Only 8 journal publications were identified concerning epidemiology and 42 articles describing JIA subtypes from Africa and Middle East [ 19 , 20 ]. The literature from Asia, especially India and Taiwan; the commonest subtype is enthesitis related arthritis.…”

Section: Discussionmentioning

confidence: 99%

Subtype frequency, demographic features, treatment and outcome of Juvenile Arthritis in one Centre in Abu Dhabi in the United Arab Emirates

2023

View full text Add to dashboard Cite

Background Juvenile Idiopathic Arthritis is a chronic inflammatory disease that affects 1 in 1000 children worldwide. Our population in the United Arab Emirates is diverse. The objective of this study is to describe the subtype frequency, demographic features and treatments received and outcome of our patients. Methods Patients with the diagnosis of Juvenile Arthritis identified through the hospital electronic medical records system (EMR), which was implemented for all medical documentation in January 2011. All patients included are patients who presented to our center for treatment and follow up from 2011 to end of 2021. Retrospective case notes review of patients electronic medical records with the diagnosis of JIA was performed. Results One hundred thirty-eight patients in total. Oligoarticular subtype was the most represented with 75 patients (55%) followed by Rheumatoid factor negative polyarticular JIA with 32 patients (23%) then Enthesitis related arthritis (ERA) with 10 patients (7%) then psoriatic (6%) then systemic JIA (5%). Undifferentiated subtype of 2%. The most diagnostic delay is in enthesitis related arthritis subtype with a mean of 11.4 months (6–25) followed by undifferentiated JIA with a mean of 7.5 months (4–8.5). 131 (96%) out of 138 received steroid treatment. Only 6 patients did not receive steroids. Out of 138 patients, 101 (73%) were on synthetic disease modifying medication methotrexate. Sixty-eight patients out of the total 138 required biologic treatment (49%). In total 93 patients achieved clinical remission (67%). In remission on treatment 78 patients which is (56%) of the total number of patients with follow up ranging from 1 to 5 years and 84% of patients in remission. In remission off treatment 15 patients (11% of all patients and 16% of patients in remission). Conclusion The most common subtype in our cohort of patients is oligoarticular JIA. Longest delay is for ERA subtype. All our patients with oligoarticular JIA received Intra articular steroid injection as first line treatment. 49% of our patients received biologic treatment similar to rate in Northern Europe. Our remission rate is 67% with 11% of patients are in remission off treatment. Access to care remains a priority to treat patients effectively.

show abstract

Section: Discussionmentioning

confidence: 99%

Subtype frequency, demographic features, treatment and outcome of Juvenile Arthritis in one Centre in Abu Dhabi in the United Arab Emirates

2023

View full text Add to dashboard Cite

show abstract

“…Thus, future multi‐center studies based on random samples are suggested. In addition, in line with epidemiological studies which found that the most JIA patients are diagnosed with Oligoarticular subtype (Al‐Mayouf, Al Mutairi, Bouayed et al ., 2021 ; Consolaro, Giancane, Alongi et al ., 2019 ), most patients (52.77%) in this study were also diagnosed with this subtype. However, the number of patients diagnosed with other JIA subtypes was insufficient to compare them in regard to their psychological tendencies.…”

Section: Discussionmentioning

confidence: 99%

“… Notes : anti‐TNF alpha = anti‐tumor necrosis factor‐alpha; JIA = juvenile idiopathic arthritis; NSAID, non‐steroidal anti‐inflammatory drug. a Most patients in this study are diagnosed with oligoarticular JIA subtype which agrees with previous epidemiological studies that showed this subtype of JIA to be the most prevalent one in the Middle East (Al‐Mayouf et al ., 2021 ), and the worldwide (Consolaro et al ., 2019 ). b The treatment type refers to the medical treatment the patients received during the study.…”

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Psychological tendencies of children with juvenile idiopathic arthritis

Badarnee

Tirosh

Kreitler

2022

Scandinavian J Psychology

View full text Add to dashboard Cite

A bulk of studies showed an association between stressful events and juvenile idiopathic arthritis (JIA) but failed to identify specific psychological tendencies that contribute to the patients' vulnerability to stress. The purpose of this paper is to identify psychological tendencies specific to JIA that would unravel characteristic sources of stress. The study is based on the cognitive orientation model of health, which enables us to identify these kinds of tendencies in terms of four belief types (beliefs about self, general beliefs, beliefs about norms, and goals) that refer to specific themes. This is a case‐control‐cohort study that included a sample of 36 patients (mean age = 12.44 years, SD = 2.97, 21 females) and 41 matched controls (mean age = 13.15 years, SD = 2.01, 22 females). The JIA cognitive‐orientation questionnaire was administered, and relevant medical parameters were recorded. The belief types differentiated between the two groups, and the patients were characterized using six themes. Examples of the themes are being over‐sensitive, striving for success, and not fulfilling duties well. The themes differentiated between the participants' groups with an accuracy of 89.1%. The likelihood of the patients being characterized by the themes is 3.24–9.35 times more than the controls. The psychological tendencies of JIA were discussed as generators of stress (e.g., being over‐sensitive) and cognitive conflicts (e.g., the contradiction between striving for success versus not fulfilling duties well). Also, the suggested reflections of these tendencies in the health workers' and patients' relationships, such as egalitarian interaction, and non‐formal communication style, were described.

show abstract

“…Juvenile idiopathic arthritis (JIA) is one of the most common chronic inflammatory rheumatic diseases of childhood [1][2][3]. Information on its prevalence in the world may vary slightly, depending on the region of residence [4][5][6]. The results of recent studies indicate that in Ukraine the incidence of JIA in children aged 0 to 17 years is…”

Section: Introductionmentioning

confidence: 99%

Clinical manifestations of gastrointestinal tract changes in children with juvenile idiopathic arthritis

Shevchenko

Pavlova

Benson

2021

Actual Problems of Modern Medicine

View full text Add to dashboard Cite

Summary. Juvenile idiopathic arthritis remains one of the most common chronic inflammatory rheumatic diseases of childhood. A significant proportion of patients experience nausea, vomiting, abdominal pain and loss of appetite with methotrexate therapy, which can significantly complicate the course of the disease. The aim was to study the clinical and anamnestic signs of liver disorders in children, depending on the manifestations of juvenile idiopathic arthritis. Materials and methods of research. The presence of gastrointestinal complaints, namely abdominal pain, loss of appetite, nausea and vomiting in 104 children with juvenile idiopathic arthritis who were treated at the State Institution "Institute of Child and Adolescent Health of the National Academy of Medical Sciences of Ukraine" was analyzed. Results. According to the results of the study, children with juvenile idiopathic arthritis had gastrointestinal complaints in 47.12%. We find out that the majority of children had gastrointestinal complains at the age of 10–13 years (55.36%, p ˂ 0.001), and at the onset of the disease after 15 years (100%, p ˂ 0.01). Young children often complained of abdominal pain and vomiting, older children complained of loss of appetite and persistent nausea, regardless of the variant, activity, duration of arthritis and the presence of methotrexate in complex therapy. It was also found that appearance of gastrointestinal complaints were observed more often at a dose of methotrexate less than 10 mg / m2 / body surface (p ˂ 0.05). Conclusions. 1. We find out that in 47.12% children with juvenile idiopathic arthritis had gastrointestinal complaints, aged 10–13 years (55.36%; p ˂ 0.001). The most amounts of complaints were common for patients older than 15 years old (p ˂ 0.01). 2. The nature of the complaints varied and depended mainly on the age of the patients. Younger children had abdominal pain and vomiting simultaneously older children had decreased appetite and nausea. The presence of complaints did not depend on the variant, activity and duration of the juvenile idiopathic arthritis. 3. According to our study complaints were not due to the presence of methotrexate in combination therapy. Children complained much more often if methotrexate dose was less than 10 mg / m2 than in the case of higher doses (p ˂ 0.05).

show abstract

Epidemiology and demographics of juvenile idiopathic arthritis in Africa and Middle East

Cited by 26 publications

References 58 publications

Subtype frequency, demographic features, treatment and outcome of Juvenile Arthritis in one Centre in Abu Dhabi in the United Arab Emirates

Subtype frequency, demographic features, treatment and outcome of Juvenile Arthritis in one Centre in Abu Dhabi in the United Arab Emirates

Psychological tendencies of children with juvenile idiopathic arthritis

Clinical manifestations of gastrointestinal tract changes in children with juvenile idiopathic arthritis

Contact Info

Product

Resources

About