Epidemiology and Genetic Diversity of Bartonella in Rodents in Urban Areas of Guangzhou, Southern China

Abstract

Bartonella spp. are gram-negative bacteria that can infect a wide spectrum of mammals. Rodents are considered to be the natural reservoir of many Bartonella species that are transmitted by various blood-sucking arthropods. The close contact between rodents and humans in urban areas increased the chance of transmitting rodent-borne Bartonella to humans. Investigation of the epidemiological characteristics of Bartonella infection in rodents is of great significance for the prevention and control of human Bartonellosis. In this study, rodents were captured to monitor the prevalence of Bartonella in urban areas of Guangzhou city. Six official or candidate species of Bartonella, including two confirmed zoonotic species, were detected with an overall prevalence of 6.4% in rodents captured herein. In addition, Rattus norvegicus was the predominant host species for Bartonella infection, and B. queenslandensis was the dominant species circulating in rodents in these areas. These results provide insights into the prevalence and genetic diversity of Bartonella species circulating in rodents in the urban areas of Guangzhou, and also urged the surveillance of rodent-associated Bartonella species in these areas.

The diverse genetic genotypes of Bartonella species circulating in rodents from Inner Mongolia, Northern China

“…In recent years, lots of studies have been performed on molecular investigations of Bartonella in rodents from China. Up to 2021, multiple Bartonella species have been detected in various provinces including Heilongjiang, Shaanxi, Fujian, Xinjiang, Henan, Zhejiang, Yunnan, Guangdong, Hainan, and Qinghai Provinces, China [23][24][25][26][27][28]. However, some of the studies are preliminary and only one single short gene fragment was analyzed.…”