Epidemiology and risk factors in osteoarthritis: literature review data from “OASIS” study

Abstract

Ostheoarthritis (OA) is a social disease characterized by pain, inflammation and stiffness due to an involvement of articular cartilage, soft tissues and bone.OA is the most common rheumatic disease, every age can be affected but prevalence increases dramatically with age with a greater incidence in subjects between 40 and 50 years of age. Hip OA has an important correlation with weight, genetic factors, sex, previous traumas, occupational factors and age. People older than 35 have a prevalence of Hip OA of 10,8% that becomes 35,4% in people older than 85. Knee OA has a great correlation with weight ,life style and physical activity. An Italian study has demonstrated that the prevalence of this kind of OA is highest in subjects older than 65 that becomes 44% in people older than 80. In this report we explain the results of a study conducted in the South of Italy called the OstheoArtrithis Southern Italy Study (OASIS) that involved 456 doctors and 1782 patients of three different regions.The mean age of these patients was 66,3 years and we evaluated prevalence of hip, knee, hand and spine OA and correlated it to sex, age, weight and BMI. We also evaluated what kind of drugs were used for these patients. Knee OA is the most common subset of OA, the one that requires the highest number of examinations and the one that causes the greatest disability.The most common used drugs are Fans and Coxibs. Condroprotectors were not used much, probably because they are not considered to be very effective

Osteoarthritis: etiology, epidemiology, impact on the individual and society and the main principles of management

“…The data of the Osteoarthritis Southern Italy Study (OASIS) involving 1782 patients in Italy demonstrated that hip OA had an important correlation with weight, genetic factors, sex, previous traumas, occupational factors, and age. Knee OA had a great correlation with weight, lifestyle (sedentary lifestyle, cultural or religious aspects of life), and physical activity (17). Similar results were obtained assessing the data of a case-control study among 101 women in Japan, and later these results were compared to the fi ndings of study in carried out in Britain.…”

Evaluation of health outcomes in osteoarthritis patients after total knee replacement: a two-year follow-up

“…OA is among the most prevalent diseases affecting adults and a major contributor to physical disability, morbidity, and utilization of health care resources worldwide[2-5]. In patients with severe knee OA who have failed conservative treatments (e.g.…”

An intervention study on the effectiveness of isometric quadriceps hamstrings exercise in the treatment of osteoarthritis, knee joint

“…Osteoarthritis (OA) is the most common type of arthritis found worldwide especially in the elderly [7] It is a disease characterized by pain and inflammation due to the involvement of the articular cartilage, soft tissues and bone [8] . Osteoarthritis is the single most common cause of disability in older adults [9] Three major physical impairments, such as knee pain, stiffness, and decreased quadriceps strength, are highly associated with a knee OA and are believed to contribute to physical disability and progression of the disease [26][27][28] As the quadriceps muscle plays the role of shock absorber, a weakness of this muscle decreases the joint protection resulting in greater stress and overload on the knee [25] .…”

“…With the population ageing, the prevalence of OA is increasing, and its consequences have a significant impact on the society. 7 It is a disease characterized by pain and inflammation due to the involvement of the articular cartilage, soft tissues and bone [8] Osteoarthritis is the single most common cause of disability in older adults [9] The 2010 Global Burden of Disease Study reports that the burden of musculoskeletal disorders is much larger than estimated in previous assessments and accounts for 6.8% of DALYs % to 15% of all adults aged over 60 have some degree of OA, with prevalence higher among women than men.4 [11] . The prevalence of OA is increasing due to population ageing and an increase in related factors such as obesity.…”