Epidemiology and Risk Factors of Functional Constipation in Pregnant Women

Shi, Wei; Xu, Xin; Zhang, Yi; Guo, Sa; Wang, Jing; Wang, Jianjun

doi:10.1371/journal.pone.0133521

Cited by 46 publications

(61 citation statements)

References 24 publications

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“…17 Shi et al showed that sedentary occupations were related to a higher prevalence of constipation. 18 Our results are consistent with most previous studies, showing that office workers, civil servants, and teachers were most commonly suffered from constipation, which are more sedentary and stressful occupations in China.…”

Section: Overview Of Constipation Treatmentsupporting

confidence: 92%

“…Our investigation showed that the top three causes of constipation as disordered eating routines, eating spicy food and failure to defecate in time. Shi et al found that eating spicy food was a risk factor for functional constipation . Kunimoto et al confirmed that ceasing to skip breakfast and suppressing bowel movements had a substantial effect on increasing bowel movement and preventing constipation .…”

Section: Discussionmentioning

confidence: 99%

“…Shi et al found that eating spicy food was a risk factor for functional constipation. 18 Kunimoto et al con-…”

Section: T a B L E 1 Participants' Characteristicsmentioning

confidence: 99%

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Clinical features and treatment options among Chinese adults with self‐reported constipation: An internet‐based survey

Song

Bai

Zhang

et al. 2019

J of Digest Diseases

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Objective We aimed to investigate the clinical features, precipitating factors, bowel habits, bothersome symptoms and treatment strategies of individuals in China with self‐reported constipation. Methods An internet‐based survey was conducted in China. The participants had self‐reported chronic constipation (≥1 symptoms including straining, hard stools, time‐consuming defecation, sensations of incomplete evacuation and anorectal blockage, using manual assistance, and fewer than three defecations per week, for over 6 months). Data on their sex, age and occupation, precipitating factors, bowel habit, main symptoms and treatment options were collected. Results Overall, 6318 participants fulfilled the inclusion criteria for chronic constipation. More women (54.6%, n = 3450) than men reported constipation. The most common age group for constipation was 31 to 40 years (40.0%, n = 2520) and the most common occupation was office workers (43.6%, n = 2754). Disordered eating routines, consuming spicy food, and failure to defecate in time were the most common factors associated with constipation. Overall, 76.0% (n = 4804) participants did not defecate in the morning; 56.2% (n = 3548) spent 6 to 15 minutes in defecating. The most prevalent symptom was straining (39.4%, n = 2489). For preferred treatment options, 81.7% (n = 5160) selected changes in their lifestyle and diet, 51.1% (n = 3229) selected using traditional Chinese medicine, and 25.2% (n = 1590) selected using laxatives. Conclusions Constipation rates were higher in women, people aged 31 to 40 years old, and those working in offices. Having eating disorders, eating spicy food and withholding stools were the most common precipitating factors. Straining was the most prevalent symptom. Lifestyle changes were the most common action taken for managing constipation.

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Section: Overview Of Constipation Treatmentsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

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Clinical features and treatment options among Chinese adults with self‐reported constipation: An internet‐based survey

Song

Bai

Zhang

et al. 2019

J of Digest Diseases

View full text Add to dashboard Cite

show abstract

“…Functional constipation is defined when there are no anatomical or physiological causing factors. It was reported as a common intestinal disorders found prevalent in elderly and middle-aged women yet younger individuals nowadays were shown with constipation due to changes in sociocultural, diet, lack of physical activity and stress factors [31, 32]. This survey was conducted to estimate the prevalence of FC among the students from tertiary education setting by using Rome III criteria.…”

Section: Discussionmentioning

confidence: 99%

“…For educational level, there were some contradictions on the research outcomes. There were studies shown that highly educated individuals have higher constipation disorders [31, 55] whereas no reported relationship was found of educational level with the occurrence of constipation [56]. These rather contradictory results may be due to different sampling method, definition used for FC, data collected either through self-report by the respondents or Rome criteria [57].…”

Section: Discussionmentioning

confidence: 99%

The Prevalence and Symptoms Characteristic of Functional Constipation Using Rome III Diagnostic Criteria among Tertiary Education Students

et al. 2016

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Background and AimsFunctional constipation is very common with heterogeneous symptoms that have substantial impact on patient quality of life as well as medical resources which are rarely reported as life-threatening. The aim of this study is to examine the prevalence and symptoms characteristic of functional constipation (FC) by using Rome III diagnostic criteria among tertiary education students with an intention to introduce treatment in the future.MethodsDemographic, socio-economics characteristics and symptoms of FC using the Rome III criteria were sought using a questionnaire administered to Malaysian students in a tertiary education setting. Other data obtained were the general health status, lifestyle factors and anthropometric measurements. Using a simple random sampling method, a total of 1662 students were recruited in the study with a response rate of 95.0%. Sampled data are presented as frequency and percentage and stratified accordingly into categories for Chi-square analysis.ResultsThe prevalence of functional constipation among the students was 16.2%, with a significantly higher prevalence among women (17.4%) than men (12.5%). Hard or lumpy stool, incomplete evacuation, anorectal obstruction and straining were reported as the commonest symptoms experienced. Type 3 was the most frequent stool consistency experienced among the constipated individuals (35.2%). Only 4.4% of individuals reported having less than three defecations per week. Using univariable analysis, FC was significantly associated with sex (odds ratio: 1.48, 95% CI: 1.06–2.06) and age group (odds ratio: 1.34, 95% CI: 1.01–1.79) with P value < 0.05 significance level. In multivariate logistic regression analysis, only sex was found significantly associated with FC (adjusted odds ratio: 1.53, 95% CI: 1.08–2.17, P < 0.05).ConclusionsBased on the prevalence rate, constipation is a common problem among tertiary education students (16.2%), with significantly more prevalence among the female respondents. Early detection of symptoms and further intervention studies focusing on treatment recommendation in improving the symptoms are essential.

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Lactiplantibacillus plantarum X7022 ameliorates loperamide‐induced constipation and modulates gut microbiota in mice

Chen

Liu

Zhao

et al. 2022

Food Bioengineering

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Lactiplantibacillus plantarum X7022 is a novel strain isolated from stinky tofu brine. Its constipation amelioration potential was evaluated on two different constipation types (acute and subacute) in mice induced by loperamide hydrochloride in present work. L. plantarum X7022 could significantly decrease the first black stool defecation time, and increase black fecal weight, number, and the gastrointestinal transit ratio in both models. High‐dose treatment of L. plantarum X7022 (2 × 1010 CFU/kg BW) was more significant in improving constipation condition than low‐dose (2 × 107 CFU/kg BW). Furthermore, 16S rDNA sequencing of the intestinal flora showed that the treatment with the strain X7022 could increase the α diversity in both constipation models. Meanwhile, the abundance of Bacteroidetes increased, and Firmicutes decreased, which was more effective in acute constipated mice. In addition, X7022 treatment could enhance the relative abundance of beneficial flora, such as Bacteroides, Ruminococcus, and depressed Adlercreutzia and Odoribacter in acute model mice. In subacute constipated mice, X7022 treatment could enhance Alloprevotell, Rikenellaceae_RC9, and decreased Lachnospiraceae_NK4A136 and Desulfovibrio. Therefore, L. plantarum X7022 is a prospect probiotic strain for the amelioration of constipation.

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Epidemiology and Risk Factors of Functional Constipation in Pregnant Women

Cited by 46 publications

References 24 publications

Clinical features and treatment options among Chinese adults with self‐reported constipation: An internet‐based survey

Clinical features and treatment options among Chinese adults with self‐reported constipation: An internet‐based survey

The Prevalence and Symptoms Characteristic of Functional Constipation Using Rome III Diagnostic Criteria among Tertiary Education Students

Lactiplantibacillus plantarum X7022 ameliorates loperamide‐induced constipation and modulates gut microbiota in mice

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