Epidemiology and Treatment of Lacrimal Gland Tumors

Abstract

Our study demonstrates that ACC is the most common malignant epithelial neoplasm of the lacrimal gland. Determinants of survival for tumors of the lacrimal gland include age at diagnosis and surgical therapy. Radiation therapy is associated with improved DSS in SCC but not in ACC.

Epidemiology, prognostic factors, and management of malignant odontogenic tumors: an analysis of 295 cases

“…Application of the SEER database to analyze patient and diseaserelated characteristics has been previously validated in several studies investigating malignancies of the head and neck. [15][16][17][18][19][20] Surgery and early detection of maliginant odontogenic tumors significantly improve patient prognosis. However, no clear survival benefits were found for radiation therapy.…”

Management of a Lacrimal Duct Tumor with Metastasis to the Thyroid

“…Most malignant lacrimal sac tumors are treated with surgery or radiotherapy, but there is no consensus for management due to its rarity [5]. A recent cohort analysis suggested that both surgery and radiotherapy improved survival in patients with SCC of the lacrimal duct [6]. However, while local invasion is common, metastases of lacrimal gland tumors are seldom reported [6].…”

“…A recent cohort analysis suggested that both surgery and radiotherapy improved survival in patients with SCC of the lacrimal duct [6]. However, while local invasion is common, metastases of lacrimal gland tumors are seldom reported [6]. One case series of 82 patients reported lymphatic metastases in 21 patients (26%), lung metastases in 4 patients and esophageal metastases in 2 patients [7].…”

“…Adenoid cystic sarcoma and squamous cell carcinoma (SCC) are the most common subtypes [6]. Here, we describe a case of a thyroid metastasis from a primary SCC of the left lacrimal sac.…”

Imaging of the Postoperative Orbit

“…5,6 The data extracted from the Surveillance, Epidemiology, and End Results database show that the best relative survival of the common orbital neoplasms, including uveal melanoma, lacrimal gland tumor, and sinonasal malignancies with orbital involvement, was noted in patients treated with surgery or a combination of surgery and chemoradiotherapy. [7][8][9][10][11] Given the multidisciplinary medical advancements in treating orbital neoplasms, there is an increasing number of survivors who require surveillance imaging to monitor local disease control and treatment response, and to detect early recurrence and guide subsequent management. [10][11][12][13] Other common orbital procedures include orbital decompression for thyroid orbitopathy and maxillofacial orbital reconstruction in the setting of trauma.…”