Epidemiology of Asthma and Allergic Diseases

Tang, Erika Avila; Matsui, Elizabeth C.; Wiesch, Denise G.; Samet, Jonathan M.

doi:10.1016/b978-0-323-05659-5.00042-5

Cited by 13 publications

(10 citation statements)

References 460 publications

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“…Allergic sensitization and accompanying specific triggers define allergic asthma, which may be the largest asthma phenotype. It is the prominent phenotype in pediatric asthma [65].…”

Section: Allergic Asthmamentioning

confidence: 99%

Asthma phenotypes in adults and clinical implications

Fajt¹,

Wenzel²

2009

Expert Review of Respiratory Medicine

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It is becoming increasingly recognized that asthma is a heterogeneous disease, whether based on clinical factors, including the patient's age at diagnosis, symptom spectrum and treatment response, triggering factors, or the level and type of inflammation. Attempts to analyze the importance of these characteristics to the clinical presentation of asthma have led to the appreciation of numerous separate and overlapping asthma phenotypes. However, these approaches are 'biased' and based on the clinician/scientist's own experience. Recently, unbiased approaches have also been attempted using both molecular and statistical tools. Early results from these approaches have supported and expanded on the clinician's concepts. However, until specific biologic markers are identified for any of these proposed phenotypes, the definitive nature of any phenotype will remain speculative.

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“…Allergic sensitization and accompanying specific triggers define allergic asthma, which may be the largest asthma phenotype. It is the prominent phenotype in pediatric asthma [65].…”

Section: Allergic Asthmamentioning

confidence: 99%

Asthma phenotypes in adults and clinical implications

Fajt¹,

Wenzel²

2009

Expert Review of Respiratory Medicine

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“…[2][3][4][5][6][7] Additionally, most epidemiologic studies focus on seasonal allergic rhinitis because of the easy identification of symptoms association with pollen exposure. First, most data regarding the true prevalence of allergic rhinitis are difficult to interpret because the majority of studies use either a physician diagnosis of disease or results from patient-administered surveys and/or phone interviews.…”

Section: Epidemiologymentioning

confidence: 99%

Allergic Rhinitis

Gentile¹,

Pleskovic²,

Bartholow³

et al. 2016

Pediatric Allergy: Principles and Practice

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“…[2][3][4][5][6][7][8][9][10][11][12] Most epidemiologic studies have been directed toward the identification of seasonal allergic rhinitis because of the easy identification of the rapid and reproducible onset and offset of symptoms in association with pollen exposure. Most population surveys rely on physician-diagnosed rhinitis for their data, possibly underestimating the actual frequency with which rhinitis occurs.…”

Section: Epidemiologymentioning

confidence: 99%

“…4 When a clear relation between onset of pollination and the typical rhinitis symptoms is present, the diagnosis of allergic rhinitis is relatively simple. This produces conjunctival irritation (itchy, watery eyes), redness and tearing, ear fullness and popping, itchy throat, and pressure over the cheeks and forehead.…”

Section: Diagnostic Testsmentioning

confidence: 99%

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Allergic Rhinitis

Gentile¹,

Skoner²

2010

Pediatric Allergy: Principles and Practice

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allergic rhinitis is found in approximately 10% of the general population and perennial rhinitis is found in 10-20% of the population. [2][3][4][5][6][7][8][9][10][11][12] Overall, allergic rhinitis affects 20 to 40 million people in the USA. 11,12 The frequency of allergic rhinitis in the general population has risen in parallel with that of all IgE-mediated diseases during the past decade. Swedish army studies have shown that the prevalence of seasonal allergic rhinitis has increased from 4% to 8% in the 10-year period from 1971 to 1981. 13 In addition, atopic skin test reactivity increased from 39% to 50% in Tucson, Arizona, during an 8-year period of testing. 5,12 The prevalence of allergic rhinitis in the pediatric population also appears to be rising. One study showed a prevalence of physician-diagnosed allergic rhinitis in 42% of 6-year-old children. 5 Another study conducted in Finland reported a near tripling of the prevalence from 1977 to 1991. 14 Currently, allergic rhinitis is the most common atopic disease and one of the leading chronic conditions in children younger than 18 years. 15 These figures relate to industrialized nations; there is generally less atopic disease in underdeveloped countries for reasons that are not entirely clear but involve genetic and environmental interactions. SexIn childhood, boys with allergic rhinitis outnumber girls, but, in general, equal numbers are affected during adulthood. AgeSymptoms of allergic rhinitis develop before the age of 20 years in 80% of cases. Children in families with a bilateral family history of allergy generally have symptoms before puberty; those with a unilateral family history tend to have symptoms later in life or not at all. 5-7 Symptoms of allergic rhinitis develop in 1 of 5 children by 2 to 3 years of age and in approximately 40% by the age of 6 years. Approximately 30% develop symptoms during adolescence. Risk FactorsStudies have shown that the frequency of allergic rhinitis increases with age and that positive allergy skin tests are significant risk factors for the development of new symptoms of allergic rhinitis. There appears to be a higher prevalence of rhinitis ©

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Epidemiology of Asthma and Allergic Diseases

Cited by 13 publications

References 460 publications

Asthma phenotypes in adults and clinical implications

Asthma phenotypes in adults and clinical implications

Allergic Rhinitis

Allergic Rhinitis

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