Epidemiology of asthma and allergic rhinitis in a total community, Tecumseh, Michigan

Broder, I.; Higgins, Millicent; Mathews, Kenneth P.; Keller, Jacob B.

doi:10.1016/0091-6749(74)90038-4

Cited by 182 publications

(27 citation statements)

References 13 publications

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“…This last effect may be due to residual confounding by active smoking after 16 years of age, which was the dominant risk factor for wheezing of later onset. Cigarette smoking is a powerful risk factor for the development of chronic mucus hypersecretion and progressive airflow obstruction in middle and old age29 but, remarkably, has not been reported in several studies of asthma incidence 14 30 31 32. The four year incidence of doctor diagnosed asthma among people aged 10-39 years in Tucson, Arizona, was three times greater among smokers than among non-smokers at the start of the observation period 33…”

Section: Discussionmentioning

confidence: 97%

Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort

Strachan

Butland

Anderson

1996

BMJ

574

376

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Objective-To describe the incidence and prognosis of wheezing illness from birth to age 33 and the relation of incidence to perinatal, medical, social, environmental, and lifestyle factors.Design-Prospective longitudinal study. Setting-England, Scotland, and Wales. Subjects-18 559 people born on 3-9 March 1958. 5801 (31%) contributed information at ages 7,11,16,23, and 33 years. Attrition bias was evaluated using information on 14 571 (79%) subjects.Main outcome measure-History of asthma, wheezy bronchitis, or wheezing obtained fiom interview with subjects' parents at ages 7, 11, and 16 and reported at interview by subjects at ages 23 and 33.Results-The cumulative incidence of wheezing illness was 18% by age 7, 24% by age 16, and 43% by age 33. Incidence during childhood was strongly and independently associated with pneumonia, hay fever, and eczema. There were weaker independent associations with male sex, third trimester antepartum haemorrhage, whooping cough, recurrent abdominal pain, and migraine. Incidence from age 17 to 33 was associated strongly with active cigarette smoking and a history of hay fever. There were weaker independent associations with female sex, maternal albuminuria during pregnancy, and histories of eczema and migraine. Maternal smoking during pregnancy was weakly and inconsistently related to childhood wheezing but was a stronger and significant independent predictor of incidence after age 16. Among 880 subjects who developed asthma or wheezy bronchitis from birth to age 7, 50% had attacks in the previous year at age 7; 18% at 11, 10% at 16, 10% at 23, and 27% at 33. Relapse at 33 after prolonged remission of childhood wheezing was more common among current smokers and atopic subjects.Conclusion-Atopy and active cigarette smoking are major influences on the incidence and recurrence of wheezing during adulthood.

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Section: Discussionmentioning

confidence: 97%

Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort

Strachan

Butland

Anderson

1996

BMJ

574

376

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“…During many years there has been a medical perception that asthma is a characteristic disease of childhood and adolescence. However, different studies have shown that elderly people are not excluded from having asthma [8, 9, 10]; in fact, asthma is more frequent in advanced age than in adulthood and new-onset asthma may occur at any age, even in the eighth and ninth decades of life [7, 11, 12]. Well-known clinical characteristics of asthma in elderly as compared with younger patients include a large number of respiratory symptoms and a more severe impairment of pulmonary function and disability [10, 11, 12, 13].…”

Section: Introductionmentioning

confidence: 99%

Quality of Life and Economic Features in Elderly Asthmatics

Plaza

Serra-Batllés²,

Ferrer³

et al. 2000

Respiration

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Background: In the geriatric population, asthma tends to be overlooked. Moreover, typical symptoms of asthma may mimic chronic bronchitis and emphysema. Objective: To compare the characteristics of asthma between elderly (≥65 years) and adult (<65 years) asthma patients with regard to asthma severity, health-related quality of life, and direct expenditures for medical care generated by the disease. Methods: A cross-sectional study was made in the asthmatic population older than 14 years in the area of Barcelona, Spain. Asthma severity was determined according to the International Consensus criteria of 1992. St. George’s Respiratory Questionnaire (SGRQ) was used to measure the quality of life. Direct costs were calculated registering all costs generated by each patient per year. Results: The study population consisted of 282 adult asthmatics and 51 elderly asthmatics. Asthma was more severe in the elderly group (mild 10%, moderate 35%, severe 55%) than in the adult group (mild 47%, moderate 35%, severe 18%). Elderly asthmatics had significantly higher total SGRQ scores (48 vs. 35, p < 0.001) than adult asthmatics, as well as significantly higher scores for all subscales. Asthma-derived direct costs in elderly asthmatics (mean USD 1,490 vs. USD 773) were double those in adult asthmatics, mainly due to higher costs of hospitalization and medication in the elderly. Conclusions: Asthma in elderly people as compared with asthma in adulthood was more severe and was associated with a worse health-related quality of life, and significantly higher expenditures for medical care.

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“…All diagnostic information has been indexed since 1935 using Berkson codes even before International Classification of Diseases (ICD) codes were available [5]. The incidence rate of asthma in Rochester was 238 per 100,000, which is comparable to those in other communities such as Tecumseh, Michigan (250/100,000) [6]. …”

Section: Methodsmentioning

confidence: 99%

Impact of Asthma on the Severity of Serious Pneumococcal Disease

et al. 2014

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We recently reported an increased risk of serious pneumococcal disease (SPD) in asthmatics. Little is known about the impact of asthma status on the severity of SPD. We compared the severity of serious pneumococcal disease (SPD) between patients with asthma and those without asthma. The study subjects were Rochester, Minnesota residents who developed SPD between 1964 and 1983. SPD and asthma status were ascertained by using explicit predetermined criteria Severity of SPD was assessed using intensive care unit (ICU) admission rate and total days of ICU stay and hospitalization associated with treatment for SPD. We found that there were no significant differences in severity outcomes between asthmatics (n=11) and non-asthmatics (n=163). Asthma status may increase the risk of SPD but not influence its severity. However, given a small sample size of our study, a larger study needs to be considered to clarify the relationship between asthma and severity of SPD.

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Epidemiology of asthma and allergic rhinitis in a total community, Tecumseh, Michigan

Cited by 182 publications

References 13 publications

Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort

Incidence and prognosis of asthma and wheezing illness from early childhood to age 33 in a national British cohort

Quality of Life and Economic Features in Elderly Asthmatics

Impact of Asthma on the Severity of Serious Pneumococcal Disease

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