261C oronary artery disease is responsible for millions of deaths per year in developed countries (1, 2). Early recognition of coronary artery disease is important for the prevention of its related complications and improving prognosis (3). Catheter angiography has been considered the gold standard imaging method for evaluating the coronary tree. The major advantages of conventional coronary angiography (CCA) are its high spatial and temporal resolutions and the option of directly performing interventions, such as balloon dilation or coronary stent placement (4). However, CCA is an invasive procedure that carries the risk of morbidity and mortality (3). In addition, CCA provides only luminal data and is limited in revealing changes in the vessel wall and the adjacent soft tissues. Conversely, multidetector computed tomography coronary angiography (MDCT-CA) not only provides visualization of the vessel lumen but also displays the vessel wall and surrounding soft tissues, allowing for the detection of various congenital or acquired abnormalities of the coronary arteries that may not be evident with CCA (3).In this article, on the basis of our experience with more than 15 000 MDCT-CA from seven different centers, we reviewed clinical conditions in which MDCT-CA may be more helpful compared with CCA.
Coronary CT techniqueWith the advent of technological refinements in the last decade, MDCT-CA has gained widespread use for the evaluation of coronary artery diseases. Currently, state-of-the-art computed tomography (CT) systems can simultaneously acquire 64 or more submillimeter sections with a gantry rotation time of less than half a second. Previous limitations of CT for evaluating the vascular system, associated with older generation scanners, have now been eliminated. Presently, a thinner section thickness allows for isotropic voxels, which is essential for optimum high-resolution, three-dimensional (3D) reconstruction and other postprocessing displays, such as maximum projection reformatting (MPR) in any selected plane. Faster scanners have resulted in shorter scans and shorter contrast bolus durations, allowing for the use of less contrast agent at a higher flow rate to achieve greater luminal enhancement. Motion artifacts from breathing are no longer a problem since highresolution imaging of the entire heart can be obtained in a single breath hold. Electrocardiography (ECG) gating techniques improve temporal resolution and minimize imaging artifacts caused by cardiac motion. With more recent technological advances, a reduction in radiation dose, for example, by the utilization of prospective gating, has occurred without any deterioration in diagnostic image quality (5).In our centers, images were acquired using either 16-or 64-MDCT scanners. Eighty-five to one hundred milliliters of iodinated contrast medium (Ultravist 370, Schering, Berlin, Germany) was intravenously ABSTRACT In this review, we aimed to outline the clinical and pathological conditions for which multidetector computed tomography coronary angiogr...