Epidemiology of knee osteoarthritis in India and related factors

Abstract

Background:Among the chronic rheumatic diseases, hip and knee osteoarthritis (OA) is the most prevalent and is a leading cause of pain and disability in most countries worldwide. Its prevalence increases with age and generally affects women more frequently than men. OA is strongly associated with aging and heavy physical occupational activity, a required livelihood for many people living in rural communities in developing countries. Determining region-specific OA prevalence and risk factor profiles will provide important information for planning future cost effective preventive strategies and health care services.Materials and Methods:The study was a community based cross sectional study to find out the prevalence of primary knee OA in India which has a population of 1.252 billion. The study was done across five sites in India. Each site was further divided into big city, small city, town, and village. The total sample size was 5000 subjects. Tools consisted of a structured questionnaire and plain skiagrams for confirmation of OA. Diagnosis was done using Kellgren and Lawrence scale for osteoarthritis.Results:Overall prevalence of knee OA was found to be 28.7%. The associated factors were found to be female gender (prevalence of 31.6%) (P = 0.007), obesity (P = 0.04), age (P = 0.001) and sedentary work (P = 0.001).Conclusions:There is scarcity of studies done in India which has varied socio geographical background and communities. We conducted this study for analyzing the current prevalence of OA in different locations. This study has evidenced a large percentage of population as borderline OA; therefore, it depends mainly on the prevention of modifiable risk factors to preserve at ease movement in elderly population through awareness programs.

Gc Globulin Gene Polymorphism: A Candidate Locus for Susceptibility to Rheumatoid and Osteoarthritis.

“…It is the joint disease caused by the breakdown of cartilage that firm rubbery tissue that cushions bones at joints. Men and women are affected but symptoms occur earlier and appear to be more severe in women [ 9]. The exact etiology of OA is unknown but it is believed that multiple factors (e.g.…”

Occupation and sports participation as risk factors for the development and progression of knee osteoarthritis

“…3 The exact etiology of knee OA remains unidentified, nevertheless, it is believed that an interplay between multiple systemic and local factors is responsible for the disorder. While systemic factors are believed to increase the vulnerability of joints to injury, local factors, which are biomechanical in nature, critically affect the forces applied to the joint.…”

Immediate effect of taping in physical performance of osteoarthritis of knee joint

“…[1,2] In India, the prevalence of the OA knee is the 28.7% more prevalent in females than in males. [3] There is no specific treatment to modify the disease. Current treatment is aimed at reducing symptoms and improving functions.…”

“…Current treatment is aimed at reducing symptoms and improving functions. [3] Analgesics and anti-inflammatory drugs are used widely, in spite of potential side effects and doubts about their efficiency, some forms of physical therapy, such as quadriceps exercises are known to be of benefit, [4] and walking aids can improve functions. Most studies have evaluated the effect of quadriceps strength on the National Journal of Physiology, Pharmacy and Pharmacology tibiofemoral joint of the knee.…”