Onychomycosis is a widespread nail disease caused by dermatophytes, yeast and non‑dermatophytes. Risk factors for the development of onychomycosis can be various somatic conditions, for example diabetes, age, lifestyle features. Often onychomycosis occurs in athletes. According to some reports, 60.7 % of football players have this disease. The reason for the increased risk of developing onychomycosis in athletes is wearing unsuitable shoes, the frequent use of synthetic clothing and sweat‑preserving shoes, and injuries to the nail plates. Preference should be given to systemic therapy. Treatment can take up to 18 months, due to the slow regrowth of a healthy nail plate. Of the systemic drugs, itraconazole is widely used. The drug can be prescribed according to the scheme of pulse therapy, and positive dynamics is observed after 2 months of use.