Epidemiology of Skin Cancer: Role of Some Environmental Factors

Fabbrocini, Gabriella; Triassi, Maria; Mauriello, Maria Chiara; Torre, G La; Annunziata, Maria Carmela; Vita, Valerio De; Pastore, Fiorella; D'Arco, V.; Monfrecola, Giuseppe

doi:10.3390/cancers2041980

Cited by 89 publications

(64 citation statements)

References 31 publications

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“…Genetic predisposition is associated with about 10% of cases, and a number of genes whose mutations are a direct cause of cancer. The best known genes associated with familial melanoma include CDK4 (12q14), P16 (9p21) and CMM1 (1p36) [22,[29][30][31].…”

Section: Discussionmentioning

confidence: 99%

Incidence of Melanoma and Non-Melanoma Skin Cancer in the Inhabitants of the Upper Silesia, Poland

Juszko-Piekut¹,

Moździerz²,

Kołosza³

et al. 2013

Highlights in Skin Cancer

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Section: Discussionmentioning

confidence: 99%

Incidence of Melanoma and Non-Melanoma Skin Cancer in the Inhabitants of the Upper Silesia, Poland

Juszko-Piekut¹,

Moździerz²,

Kołosza³

et al. 2013

Highlights in Skin Cancer

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“…Acute ozone exposure depletes skin vitamins C and E and induces lipid peroxidation in upper epidermal layers [74]. The dramatic increase of basal and squamous cell skin cancer in the past few years has been associated with stratospheric ozone depletion caused by ozone depleting substances (ODS) of anthropogenic origin and resultant higher UV-B radiations [75].…”

Section: Pollution and Its Effect On The Skinmentioning

confidence: 99%

Potential Use of Spin Traps to Control ROS in Antipollution Cosmetics—A Review

Sawant¹

2018

Cosmetics

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Abstract:Pollution from air and sunlight has adverse effects on human health, particularly skin health. It creates oxidative stress, which results in skin diseases, including skin cancer and aging. Different types of antioxidants are used as preventative actives in skin-care products. However, they have some limitations as they also scavenge oxygen. Recently, spin traps are being explored to trap free radicals before these radicals generating more free radicals (cascading effect) and not the oxygen molecules. However, not all spin traps can be used in the topical cosmetic skin-care products due to their toxicity and regulatory issues. The present review focuses on the different pathways of reactive oxygen species (ROS) generation due to pollution and the potential use of spin traps in anti-pollution cosmetics to control ROS.

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“…Directly, increased exposure to ultraviolet B (UVB) radiation resulting from depletion of stratospheric O3 has been reported to cause basal and squamous cell skin cancer. Furthermore, increased temperatures due to climate change may lead to skin cancers [34] . Indirectly, high temperatures encourage inactive lifestyle, which leads to obesity, important risk factors for cancer.…”

Section: Climate Change and Cancersmentioning

confidence: 99%

Untitled

2017

RJLBPCS

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ABSTRACT:Climate change through its effect on weather, anthropogenic emissions, distribution and types of air irritants is expected to increase exposure to air pollutants such as Carbon monoxide, Sulphur dioxide and Ozone. In addition, climate change is proposed to increase the risk of cardiovascular diseases (CVDs) directly through air pollution, extreme temperatures and indirectly via changes in diets. This is projected to increase morbidity and mortality from NCDs tremendously in low and middle income Countries. The purpose of this study was to review existing literature on impact of climate change on NCDs, identify gaps in existing studies, to stimulate further research interest in the field. This was a literature survey in which PubMed, ScienceDirect and Google scholar databases were searched using keywords; Climate change, Mitigation, Health, Non-Communicable Diseases, Diabetes, Cancers and Cardiovascular diseases (CVDs). Little research has been done on climate change and NCDs; therefore, data is lacking or inadequate if at all. Out of a total of 3,204,565 hits only 65,815 articles were specific to climate change and health, out of which only 35 were directly relevant to the survey. Results from this review indicated that climate change has led to increased or extreme temperatures, which can be directly or indirectly attributed to the increased NCDs prevalence. Furthermore, inhalation and or exposure to acute ozone exposure leads to oxidative stress, inflammation, ultimately leading to diabetes mellitus I & II, CVDs and cancers.Oxidative stress is also associated with DNA damage, endothelium dysfunction, damage to blood cells leading to high blood pressure, arteriosclerosis, myocardial infarction among other cardiovascular conditions. However, further research is required to strengthen this hypothesis. This information will help in attainment of sustainable development goal (SDG) number 3 on ensuring health for all, promotion of wellbeing for all at all ages and number 13 on combating climate

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Epidemiology of Skin Cancer: Role of Some Environmental Factors

Cited by 89 publications

References 31 publications

Incidence of Melanoma and Non-Melanoma Skin Cancer in the Inhabitants of the Upper Silesia, Poland

Incidence of Melanoma and Non-Melanoma Skin Cancer in the Inhabitants of the Upper Silesia, Poland

Potential Use of Spin Traps to Control ROS in Antipollution Cosmetics—A Review

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