Epidemiology of the Rheumatic Diseases in Mexico. A Study of 5 Regions Based on the COPCORD Methodology

Peláez‐Ballestas, Ingris; Sanı́n, Luz Helena; Moreno‐Montoya, José; Álvarez-Nemegyei, José; Burgos‐Vargas, Rubén; Garza‐Elizondo, Mario Alberto; Rodríguez-Amado, Jacqueline; Goycochea-Robles, María Victoria; Madariaga, Marco A.; Zamudio, Jorge A.; Santana, N.; Cardiel, Mario H.

doi:10.3899/jrheum.100951

Cited by 235 publications

(133 citation statements)

References 16 publications

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“…It is noteworthy that the study population was very representative of the Brazilian population according to the IBGE census of 2010. Epidemiological studies describing the frequency, distribution, and determining factors of diseases are an important initial strategy to design policies regarding disease prevention and management [12]. The use of the CQ has proved to be a useful tool for detecting cases of rheumatic diseases with the possibility to designate those patients as soon as possible to a rheumatologist or set priorities in the primary care setting [13,14].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of musculoskeletal symptoms in the five urban regions of Brazil—the Brazilian COPCORD study (BRAZCO)

et al. 2015

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The objective of this study is to describe the prevalence of musculoskeletal symptoms (MSK-S) in the five urban geographical regions of Brazil using the Portuguese version of the Community Oriented Program for Control of Rheumatic Diseases (COPCORD) core questionnaire (CQ)-BRAZCO study. From April to May 2013, a population-based survey was conducted by applying the CQ for 5000 individuals aged over 15 years in 16 capitals of the Brazilian regions. Trained teams assessed the MSK-S and socioeconomic status. The sample consisted of representative quotas of the Brazilian population, proportional to the capitals' population density. It respected the groups' quotas of gender and age and included all socioeconomic classes, educational levels, and occupations. There were 1342 (26.9 %) participants who presented MSK-S unrelated to trauma in 7 days preceding the interview. A higher prevalence of these complaints were in females (65.2 %), elderly people, in the north region of the country (30.7 %), and a lower prevalence was found in single individuals (41.7 %) and in the south (23.3 %). The most frequent pain sites were the spine (76.7 %) and knees (49.6 %), and the mean pain intensity was 6.8 (VAS). The BRAZCO study shows that Brazilian population presents a higher rate of MSK-S unrelated to trauma than many Asian countries. These results can be applied to guide the assessment of prevalence of rheumatic diseases. Additionally, it can help in the design of policies for health care workforce organization and its accessibility, as well as to reduce the risk of rheumatic diseases at the community level.

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Section: Discussionmentioning

confidence: 99%

Prevalence of musculoskeletal symptoms in the five urban regions of Brazil—the Brazilian COPCORD study (BRAZCO)

et al. 2015

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“…This is a secondary analysis of the database of a previously published study on the prevalence of musculoskeletal (MSK) symptoms and rheumatic conditions, including OA, carried out in the Mexican population [9]. Briefly, the study was cross-sectional and included communities from the states of Nuevo Leon, Sinaloa, Yucatan, and Mexico City.…”

Section: Methodsmentioning

confidence: 99%

“…A more detailed analysis of the data showed wide geographic variations, ranging from 2.5 to 16.3 %, which were not easily explained by methodological and individual characteristics. Nonetheless, because we carried out our study in geographical regions with uneven socioeconomic indicators [9], we hypothesized that social inequity could play a role in the prevalence of OA in each of the geographic areas studied. The approach of these geographic variations was based on a multilevel contextual design, which is able to detect social inequalities in health.…”

Section: Introductionmentioning

confidence: 99%

The Social Gap Index and the prevalence of osteoarthritis in the community: a cross-sectional multilevel study in Mexico

et al. 2014

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Multilevel studies have gained importance for highlighting social inequalities in health. These associations have been reported previously in diseases such as arthritis and chronic pain. We conducted a cross-sectional study using multilevel analysis to identify individual and contextual factors associated with the variation of prevalence of osteoarthritis (OA) in the Mexican population. The sample included 17,566 individuals of which 10,666 (60.7%) were women. The relationship between individual and contextual factors and OA were analyzed with a multilevel strategy. From the total population, 1,681 individuals had OA. Multilevel analysis showed that individual variables such as female gender (odds ratio (OR) = 1.3, 95% confidence interval (CI) 1.1, 1.4), age range 55-65 years (OR = 1.6, 95% CI 1.3, 2.0), musculoskeletal pain in the last 7 days (OR = 2.6, 95% CI 2.3, 3.0), and use of pain treatments (OR = 1.4, 95% CI 1.2, 1.7) were associated with OA. At the regional level, the Social Gap Index (SGIx) was associated with the diagnosis of OA (coefficient 0.5, 95% CI 0.2-1.1). The SGIx contextual variable was positively associated with the regional prevalence of OA and the variation in prevalence of OA in different regions. The larger the social gap, the greater the variation in OA prevalence. These factors were independently associated with the prevalence of OA: female gender, pain intensity, physical limitation, and the use of pain treatments were individual variables associated with OA. The association between OA prevalence and regional variations with SGIx reflects inequities in health provisions that should be considered in health programs.

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“…1 En México se ha reportado una prevalencia de 0.06% para esta enfermedad; la incidencia se ha estimado entre 1.8 y 7.6 casos por cada 100,000. 2 La supervivencia a los 5 años postdiagnóstico ha mejorado de forma progresiva, probablemente debido a una mejor comprensión de la enfermedad, a la aparición de nuevas terapias inmunosupresoras y de mejores tratamientos para el control de los daños.…”

Section: Introductionunclassified

Características clínicas y comorbilidades de pacientes con lupus eritematoso sistémico en niños y adultos

Alvarado¹,

Saiz²,

Cruz³

2018

Acta Pediatr Mex

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Este artículo debe citarse comoCoronado-Alvarado CD, Gámez-Saiz IL, SoteloCruz N. Características clínicas y comorbilidades de pacientes con lupus eritematoso sistémico en niños y adultos. Acta Pediatr Mex. 2018;39(1):1-12. Recibido: 20 de octubre del 2016 Aceptado: 4 de abril del 2017Resumen INTRODUCCIÓN: el lupus eritematoso sistémico es una enfermedad autoinmune crónica; se presenta mayormente en mujeres en etapa reproductiva y es menos frecuente en niños.OBJETIVO: comparar las manifestaciones clínicas, comorbilidades y farmacoterapia en niños y adultos con lupus eritematoso sistémico (LES). MATERIAL Y MÉTODOS:se seleccionaron 127 expedientes clínicos de pacientes con diagnóstico de LES; 36 menores de edad de un hospital pediátrico (grupo A) y 91 adultos de un hospital general (grupo B). Recolectamos información respecto a las manifestaciones clínicas al diagnóstico en los niños y adultos, así como las comorbilidades relacionadas y mortalidad, atendiendo los criterios de la American College of Rheumatology, también del tipo de medicamentos empleados. Estadísticas utilizadas: cálculo de frecuencias, porcentajes, la prueba de ji cuadrada, prueba exacta de Fisher, razón de momios e intervalos de confianza.RESULTADOS: en niños predominaron: eritema malar (p = < 0.01), vasculitis (p < 0.01), fotosensibilidad (p < 0.01), síndrome nefrítico (p < 0.01), alteraciones leucocitarias (p < 0.01), derrame pleural, anemia, derrame pericárdico, sepsis y hepatopatía; además, el número de medicamentos empleados fue mayor. En adultos predominaron: artralgia (p < 0.01), pancitopenia (p = 0.025), alopecia (p < 0.01), sinovitis (p = 0.044) y falla renal crónica (p = 0.04). Los fármacos usados en el grupo A fueron: hidroxicloroquina (p < 0.01), glucocorticoides (p = 0.14) y micofenolato (p = 0.28), la mortalidad en niños fue de 25% y en 91 adultos ocurrió en 5 (0.05%).CONCLUSIONES: las manifestaciones clínicas en niños muestran mayor lesión cutánea inicial y vasculitis, daño renal, cardiovascular, pulmonar e infecciones; en los adultos predominan afecciones articulares y falla renal crónica. Los niños reciben mayor número de fármacos y su mortalidad es mayor.PALABRAS CLAVE: lupus eritematoso sistémico, manifestaciones clínicas, niños, adultos.

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Epidemiology of the Rheumatic Diseases in Mexico. A Study of 5 Regions Based on the COPCORD Methodology

Abstract: The prevalence of MSK pain in our study was 25.5%. Geographic variations in the prevalence of MSK pain and specific diagnoses suggested a role for geographic factors in the prevalence of rheumatic diseases.

Cited by 235 publications

References 16 publications

Prevalence of musculoskeletal symptoms in the five urban regions of Brazil—the Brazilian COPCORD study (BRAZCO)

Prevalence of musculoskeletal symptoms in the five urban regions of Brazil—the Brazilian COPCORD study (BRAZCO)

The Social Gap Index and the prevalence of osteoarthritis in the community: a cross-sectional multilevel study in Mexico

Características clínicas y comorbilidades de pacientes con lupus eritematoso sistémico en niños y adultos

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