Epidemiology of Thyroid Lesions in Wardha District of Central India

Shukla, Samarth; Acharya, Sourya; Pansey, Parijat; Dawande, Pratibha; Tamhane, Ankita

doi:10.18410/jebmh/2015/114

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…The prevalence of these thyroid disorders varies widely according to geographical distribution, diet and nutrition, and patient population [ 1 , 2 ]. Thyroiditis a diverse group of disorder characterized by thyroid inflammation and have different etiologies [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Cytomorphological Spectrum of Thyroiditis: A Review of 110 Cases

Chandanwale

Nair

Gambhir

et al. 2018

Journal of Thyroid Research

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Introduction Different types of thyroiditis may share some parallel clinical and biochemical features. Timely intervention can significantly reduce morbidity and mortality. Aim Aim of this study is to find the frequency of various thyroiditis, study the cytomorphological features and correlate with clinical findings including radiological findings, thyroid function test, and anti-thyroid peroxidase antibodies (Anti-TPO antibodies). Materials and Methods The study included consecutive 110 cases of thyroiditis. Detailed cytomorphological features were studied and correlated with ultrasonography findings, thyroid function test, anti-thyroid peroxidase antibodies (anti-TPO) and histopathological features where thyroidectomy specimens were received for histopathological examination. Results The majority were Hashimoto's thyroiditis (n = 100) and females (n = 103). Other forms of thyroiditis were Hashimoto's thyroiditis with colloid goiter (n = 5), De Quervain's thyroiditis (n = 3), and one case each of postpartum thyroiditis and Hashimoto's thyroiditis with associated malignancy. The majority of patients were in the age group of 21–40 (n = 70) and the majority (n = 73) had diffuse enlargement of thyroid. The majority of patients were hypothyroid (n = 52). The serum anti-TPO antibodies were elevated in 47 patients out of 71 patients. In the 48 patients who underwent ultrasonography, 38 were diagnosed as having thyroiditis. The most consistent cytomorphological features seen in fine-needle aspiration smears of Hashimoto's thyroiditis were increased background lymphocytes, lymphocytic infiltration of thyroid follicular cell clusters, and Hurthle cells. Conclusion The diagnostic cytological features in Hashimoto's thyroiditis are increased background lymphocytes, lymphocytic infiltration of thyroid follicular cell clusters, and Hurthle cells. FNAC remains the “Gold Standard” for diagnosing Hashimoto's thyroiditis. Clinical history, thyroid function, and biochemical parameters are the key for diagnosis of other forms of thyroiditis.

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Section: Introductionmentioning

confidence: 99%

Cytomorphological Spectrum of Thyroiditis: A Review of 110 Cases

Chandanwale

Nair

Gambhir

et al. 2018

Journal of Thyroid Research

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“…According to a study done in Colombia (2018) the prevalence of thyroid stimulating hormone (TSH) was 24.5%, 19% of people had a high prevalence of this hormone, being higher in women (Carmona Carmona et al, 2018). Moreover, Indian study for the prevalence of thyroid disorders in 2015 reported that, almost one-third of the world's population lives in areas of iodine deficiency and account for an estimated 200 million cases worldwide and 42 million cases in India itself (Shukla et al, 2015).…”

Section: Introductionmentioning

confidence: 99%

Effect of Health Teaching Handouts on Patient’s Outcome Who Undergoing Thyroidectomy in General Surgical Departments at Mansoura University Hospitals

Ibrahim

Shereif

Hassanein

et al. 2020

Mansoura Nursing Journal

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Background: About 200 to 800 million people in the world have some form of thyroid disease (Vanderpump, 2011). Aim: The current study aimed to examine the effects of health teaching handouts on patients' outcome who undergoing thyroidectomy in General Surgical Departments at Mansoura University Hospitals. Design: A quasi experimental research design was used. Setting: This study was conducted at the General Surgical Departments at Mansoura University. Subjects: Purposive sample was used and consist of forty-two patients. Tools: Assessment Questionnaire Sheet. It was consisted of three parts to measure the following; general characteristics, the past and present history, and patient knowledge about discharge care. Findings: The majority of the studied patients have poor knowledge about thyroidectomy care pre using of the health teaching handouts, whereas, more than half of the studied patients have fair knowledge about thyroidectomy care post using of the health teaching handouts. There is a highly significant relation between patient's knowledge post using health teaching handouts on thyroidectomy care. Recommendations: Simple handouts as booklets and brochures about thyroidectomy care should be developed and distributed at the surgical units. Evidence-based thyroidectomy care guidelines should be integrated in medical surgical courses curriculum for nursing students.

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“…The prevalence of thyroid disorders varies widely according to geographical distribution, diet, nutrition, and patient population. 2,3 Thyroiditis is a diverse group of disorder characterized by thyroid inflammation and have different aetiologies. 4 It can be categorized as acute, subacute or chronic forms.…”

mentioning

confidence: 99%

Diagnostic Efficacy of FNAC along with Assay of Thyroid Hormones and Thyroid Peroxidase Antibodies in Chronic Thyroiditis

Joseph¹,

Ajitha²

2019

jebmh

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BACKGROUND The incidence of chronic thyroiditis is on the rise in our state. Chronic thyroiditis is an autoimmune disease of thyroid gland that destroys the thyroid cells and is characterised functionally by the production of autoantibodies which alter thyroid function. It is the more common in females and is the main cause of hypothyroidism. Patient usually presents with a diffuse thyroid swelling. Radiological findings are usually not very specific. HT patients usually have high levels of serum thyroid autoantibodies which include antithyroid peroxidase (anti-TPO) and antithyroglobulin (anti-Tg), 1 whereas a percentage of patients (10-15%) may be antibody negative. An increase in the serum thyroid stimulating hormone (TSH), in any phase of the disease, heralds incipient hypothyroidism. A confirmative diagnosis is usually reached only after surgery. METHODS Of the total 717 Thyroid FNACs done, 150 were diagnosed as chronic lymphocytic thyroiditis. The grading of the thyroiditis was done by the criteria used by Bhatia et al. Clinical history, ultrasonography findings, serum T3, serum T4, and thyroid stimulating hormone (TSH) and anti-TPO antibodies were noted and correlated with FNAC features. RESULTS A total of 150 chronic lymphocytic thyroiditis cases were studied. Majority was female with Female: Male ratio of 143:7. The most common age group was 41-50 yrs. and majority of them presented with nodular disease. Majority cases (45.33%) showed Grade 2 cytomorphological features of chronic thyroiditis, among them majority of the patients were euthyroid and 20% hypothyroid. 11 cases showed elevated Anti-TPO levels. Majority of cases with Grade 3 & Grade 4 thyroiditis had elevated Anti-TPO levels. CONCLUSIONS From the present study we conclude that despite of different diagnostic modalities available for diagnosis of thyroid conditions, FNAC still remains the gold standard method. Grading of FNAC material based on lymphocytic infiltration of thyroid follicles along with Positivity for antithyroid antibodies (anti-TPO antibody) is strongly associated with HT but no correlation was observed between the grades of thyroiditis and TSH. Hence, FNAC findings along with thyroid hormone and thyroid peroxidase antibody assay is very helpful in diagnosing a case of chronic lymphocytic thyroiditis.

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Epidemiology of Thyroid Lesions in Wardha District of Central India

Cited by 3 publications

References 15 publications

Cytomorphological Spectrum of Thyroiditis: A Review of 110 Cases

Cytomorphological Spectrum of Thyroiditis: A Review of 110 Cases

Effect of Health Teaching Handouts on Patient’s Outcome Who Undergoing Thyroidectomy in General Surgical Departments at Mansoura University Hospitals

Diagnostic Efficacy of FNAC along with Assay of Thyroid Hormones and Thyroid Peroxidase Antibodies in Chronic Thyroiditis

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