Epidemiology of venous thromboembolism in a Chinese population

Abstract

Venous thromboembolism is not as common in Chinese as in Caucasians, but it is certainly not rare. The majority of DVTs and PEs, however, were not associated with surgery, so routine thromboprophylaxis may not be required.

Age-associated developmental changes in the activated partial thromboplastin time (APTT) and causes of prolonged APTT values in healthy Chinese children

“…This situation necessitates the generation of several appropriate age-dependent reference ranges to interpret laboratory data in pediatric patients and prevent misclassification of children having defects of factors and inhibitors of the coagulation system (7). Since there are differences in the hemostatic system among different racial/ethnic groups (10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27), and also between different analyzer and reagent systems (4), coagulation laboratories should develop age-related reference ranges specific to their own testing systems for the local population (4,7,32). In this study, we analyzed retrospectively the results of preoperative APTT testing in childhood and adult controls undergoing minor elective surgery.…”

“…For example, the incidence and risk of venous thromboembolism (VTE) is markedly lower in Asian/Pacific Islanders than in Caucasians and African Americans (10)(11)(12)(13)(14). VTE is not as common in Chinese as in Caucasians (15). Genetic risk factors related to VTE in Caucasians such as factor V Leiden and prothrombin G20210A mutations are rare in Asian, especially in Chinese and Japanese (16)(17)(18)(19)(20)(21)(22).…”

Epidemiology and Risk Factors for Venous Thrombosis

“…There is little information on epidemiology of thrombosis in Africa. Two recent reports suggested that rates of hospitaltriggered DVT or postoperative DVT were similar in Asian and in Western countries (10,11), although the population rate of DVT in China has been estimated at only 0.17 per 1000 annually (12). The findings of the former two studies might be explained by an increased frequency of asymptomatic episodes detected by screening, and further work is needed to determine the clinical significance.…”

Clinical characteristics and laboratory findings of 252 Chinese patients with anti-phospholipid syndrome: comparison with Euro-Phospholipid cohort

“…For examples, the incidences per 100,000 of venous thrombosis were, respectively, 104 in the Caucasians and 21 in Asian-Pacific Islanders (P < 0.001) [20]. Moreover, the annual incidences per 100,000 Chinese of DVT and PE were, respectively, 17.1 and 3.9 [21].…”