INTRODUCTIONTriclosan (TCS, 5-chloro-2-(2,4-dichloro phenoxy) phenol) is described as a broadspectrum antimicrobial agent and has antibacterial and antifungal properties (Ciba Speciality Chemicals., 2001). TCS is a typical antibacterial compound present in household cleaners, and other consumer goods (McMurry et al., 1998). It is a bacteriostatic agent at small doses due to its harmful effect on bacterial enzymes responsible for the composition of the cell membrane and cell wall fatty acids. TCS interrupts the bacteria membrane at high concentrations, trying to kill it (Fahimipour et al., 2018;Jing et al., 2020). TCS, which was developed in 1972 as an antibacterial factor in a surgical scrub composition, has a similar structure to the chemical diphenyl ether group and is well-tolerated and safe. Since then, it has become one of the most common preservatives in a wide variety of products including cleaning agents, soap, shampoo, detergent, toothbrushes, rinses, and textiles for many consumers. Due to extensive environmental contamination and its identification in streams and wild animal bodily fluids, TCS usage was rapidly expanded in the last 20 years. (Rodricks et al., 2010).