Epidemiology, Pathophysiology, Causes, Morphology, and Visual Effects of Cataract

Wevill, Mark

doi:10.1016/b978-0-323-04332-8.00073-1

Cited by 7 publications

(14 citation statements)

References 34 publications

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“…How the intervention might work-Oxidation of lens proteins and mitochondrial function are key factors in cataract pathogenesis (Wevill 2008). Beta-carotene is known to be an effective antioxidant at low partial pressures of oxygen, as exists in the lens (Burton 1984).…”

Section: Plain Language Summarymentioning

confidence: 99%

Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract

Mathew

Ervin

Tao

et al. 2012

Cochrane Database of Systematic Reviews

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DIFFERENCES BETWEEN PROTOCOL AND REVIEWCochrane methodology regarding assessments of the risk of bias in included studies has been modified and the review authors updated the 'Assessment of risk of bias in included studies' section of the methods to reflect updated methodological considerations. HHS Public Access AbstractBackground-Age-related cataract is a major cause of visual impairment in the elderly. Oxidative stress has been implicated in its formation and progression. Antioxidant vitamin supplementation has been investigated in this context.

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Section: Plain Language Summarymentioning

confidence: 99%

Antioxidant vitamin supplementation for preventing and slowing the progression of age-related cataract

Mathew

Ervin

Tao

et al. 2012

Cochrane Database of Systematic Reviews

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“…The World Health Organization estimated there were 161 million visually impaired people worldwide in 2002, with cataract accounting for 47.8% of cases and the incidence of cataract increasing with age. In developing countries, cataracts occur earlier in life and the incidence is higher (2) . Highly myopic eyes tend to develop cataracts earlier than normal ABSTRACT Purpose: To evaluate the outcomes and complications following phacoemulsification surgery in eyes with cataract and high myopia.…”

mentioning

confidence: 99%

Phacoemulsificatıon in eyes with cataract and high myopia

Çetinkaya

Acır²,

Cetinkaya³

et al. 2015

Arquivos Brasileiros De Oftalmologia

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High myopia is a common condition worldwide, defined as an axial length of ≥26.0 mm. The frequency of vitreous and retinal degenerations, such as liquefied vitreous, posterior vitreous detachment, lattice degeneration, retinal holes, and retinal tears, is higher in patients with high myopia than in the general population (1) . The World Health Organization estimated there were 161 million visually impaired people worldwide in 2002, with cataract accounting for 47.8% of cases and the incidence of cataract increasing with age. In developing countries, cataracts occur earlier in life and the incidence is higher (2) . Highly myopic eyes tend to develop cataracts earlier than normal ABSTRACT Purpose: To evaluate the outcomes and complications following phacoemulsification surgery in eyes with cataract and high myopia. Methods: We retrospectively evaluated the data of 43 eyes of 28 consecutive patients (12 males, 16 females) with cataract and high myopia who had undergone phacoemulsification and intraocular lens (IOL) implantation. The mean [± standard deviation (range)] age of the patients was 59.20 ± 11.08 (39-77) years. Results: The frequency of nuclear cataract was significantly higher than that of other cataract types (P=0.003). The mean axial length was 28.97 ± 1.99 (26-33) mm and the mean IOL power was 5.09 ± 4.78 (-3.0 to +14.0) diopters (D). The mean preoperative spherical equivalent (SE) was -16.48 ± 5.23 (-8.00 to -25.00) D and the mean postoperative SE was -1.46 ± 0.93 (0.00 to -3.00) D (P=0.00). The mean preoperative best-corrected visual acuity (BCVA) was 0.91 ± 0.37 (0.30 to -1.50) logMAR and the mean postoperative BCVA was 0.29 ± 0.25 (0.00-1.00) logMAR (P=0.00). Twenty-two eyes (51.2%) achieved the target postoperative refraction (±1.0 D). The eyes were divided into 3 groups according to the axial length. The mean biometric error was significantly higher in the group with the greatest axial length than in the other groups (P=0.007). Preoperative argon laser photocoagulation was performed in 7 eyes (16%) on account of retinal tears, retinal holes, or lattice degeneration. Postoperatively, retinal tears developed in 2 eyes (4%) and were treated with photocoagulation. One eye (2%) developed retinal detachment postoperatively, with the patient consequently referred for retinal surgery. Postoperatively, posterior capsule opacities developed in 11 eyes (25%), with all cases treated by laser capsulotomy. Conclusions: Good postoperative outcomes following phacoemulsification surgery were observed in patients with cataract and high myopia. However, clinicians should be aware of the risk of postoperative retinal tears and rhegmatogenous retinal detachment. Preoperative prophylactic argon laser photocoagulation treatment should be considered where necessary.

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“…Die Linse ist hierbei meist klein, scheibenförmig ("diskoid") und meist aufgrund einer Linsenkondensation komplett eingetrübt. Weibliche Träger können fokale kortikale Punkttrübungen aufweisen [28]. Das Alport-Syndrom ist eine dominant, rezessiv oder Xchromosomal vererbte Krankheit, die eine hämorrhagische Nephropathie und sensorineurale Taubheit verursachen kann.…”

Section: Linsentrübungen Bei Seltenen Erkrankungenunclassified