Epidermal Nevus Syndrome: A Review and Case Report

Er:YAG Laser Treatment of Verrucous Epidermal Nevi

“…The elimination of verrucous epidermal nevi by ablative laser devices has been suggested by several investigators. [7][8][9][10][11][12][13] Several studies have been performed using CO 2 lasers either in the pulsed mode or the continuous-wave mode. 7-11 Ratz et al 8 first reported treatment of verrucous epidermal nevi with continuous-wave CO 2 laser.…”

“…It has been reported that at least a partial dermal excision is needed to prevent recurrence. 1,3,4,6,8,9,11 Therefore, for removal of all epidermal nevi, the entire lesions should be ablated in several passes down to the underlying uninvolved tissue.…”

“…4,5 Reported surgical therapies include liquid nitrogen, dermabrasion, surgical excision, ruby laser, 585-nm flashlamp-pumped pulsed-dye laser, argon laser, CO 2 laser, and the Er:YAG laser. [5][6][7][8][9][10][11][12][13] Surgical excision has been advocated as the most reliable therapy, but it results in a permanent scar. 1,6 In reviewing the literature, there are only two articles aimed specifically at Er:YAG treatment of epidermal nevi, 12,13 and because of short-term follow-up and the small series of treated patients, it is difficult to evaluate the efficacy and safety of Er:YAG laser in the treatment of verrucous epidermal nevi.…”

CO2Laser Treatment of Epidermal Nevi: Long-Term Success

“…Many therapies have been attempted, including intralesional and topical steroids, topical and systemic retinoids, topical 5-fluorouracil, podophyllin, dermabrasion, cryotherapy, and excisional surgery. 5,6 However, these treatment options tend to either fall short of complete eradication of the nevus or result in an unacceptable scar that can be as disfiguring as the nevus itself.…”

Epidermal naevi associated with extrahepatic portal venous obstruction, hypoplastic kidney and lymphangiectasia: a new syndromic variant?

“…There is no effective treatment for the systemic manifestations; however, epidermal naevi can be safely and effectively treated with carbon dioxide laser ablation 10 . Renal anomalies are already known as a systemic manifestation of ENS, but it remains unknown whether the EHPVO in our patient is just a chance occurrence or whether it represents a previously unrecognized association of ENS.…”