Epidermotropic Urothelial Carcinoma Involving the Glans Penis

Epidermotropic metastasis from vulvar squamous cell carcinoma: A rare cutaneous manifestation

“…16 Other case reports of epidermotropic metastases have been from eccrine porocarcinoma, Merkel cell carcinoma, primary cutaneous SCC, melanoma, other adnexal neoplasms, SCC of the vagina, hypopharyngeal carcinoma, urothelial carcinoma and colorectal carcinoma. [15][16][17][18][19][20][21][22][23][24] The histopathologic diagnosis in this case could only be attributed to metastatic disease, given the history and clinical information. As mentioned above, cutaneous metastases can be indistinguishable from primary disease.…”

Penile Preservation Surgery in a Case of Extramammary Paget's Disease Involving the Glans Penis and Distal Urethra

“…Six of 8 cases (75%) 4,5,9,11,12 with Type 3 EMPD involving the glans penis died of the disseminated primary tumor within a year. For 9 of the cases, local treatment was mentioned: 6 cases were treated with penectomy, 4,5,9,10,12,13 2 cases with resection, 6,7 and 12 3 Prostate cancer Partial penectomy 1 year Dead Turner 5 3 Bladder cancer Amputation 1 year Dead Metcalf 6 3 Bladder cancer Resection NS NS Powell 7 3 Bladder cancer Resection NS NS Tomaszewski 8 3 Bladder cancer YAG laser ablation 1 year Alive Jenkins 9 3 Bladder cancer Circumferential excision 6 months Dead Smith 10 3 Bladder cancer Partial penectomy 4 years Alive Salamanca 11 3 1 case with laser ablation. 8 The role of laser ablation in EMPD is still not defined because the follow-up time is insufficient to assess the success rate of this modality.…”

“…The standard therapy of EMPD is excision to subcutaneous tissue deep enough to remove all cutaneous adnexal structures. EMPD involving the glans penis is very rare: to our knowledge, in the English language journals accessible via MEDLINE, only 11 cases [4][5][6][7][8][9][10][11][12][13] have been reported of 150 cases of male genital EMPD. The standardized treatment of this condition, therefore, has not been well discussed, with up to 60% of reported cases treated with penectomy.…”

“…2 Secondary EMPD is defined as involvement of the genital skin by noncutaneous internal malignancies such as anal or rectal adenocarcinoma 3 and transitional cell carcinoma of the urethra or bladder. [4][5][6][7][8][9][10][11] Primary EMPD is generally a slow-growing malignancy and considered to be a relatively benign disease. The standard therapy of EMPD is excision to subcutaneous tissue deep enough to remove all cutaneous adnexal structures.…”

Exudative discoid and lichenoid chronic dermatosis (Sulzberger‐Garbe): presentation with a puzzling penile plaque*

“…A primary carcinoma of other organs must be searched for. for instance transitional eell earcinoma of the urinary bladder with extension to the urethra and glans penis [10].…”