Epidural anesthesia for the patient with type IV spinal muscular atrophy -A case report-

Kim, Seon Jin; Kim, Sang Hyun; Min, Byung Woo; Ban, Jong Seouk; Lee, Sang Gon; Lee, Ji‐Hyang

doi:10.4097/kjae.2010.59.s.s65

Cited by 5 publications

(6 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Muscle atrophy, poor tone, and weakness are hallmarks of the disease. Ultimately, patients are unable to effectively clear secretions and respiratory insufficiency ensues 17 …”

Section: Spinal Muscular Atrophymentioning

confidence: 99%

“…Providing effective postoperative pain control, while also minimizing opioid needs, is crucial to improving the chances of extubation after general anesthesia in this population. Even though opioids may further decrease respiratory drive, inadequate analgesia can result in splinting that limits chest wall excursion and re‐recruitment of atelectatic lung 17 . Although prolonged respiratory support after general anesthesia is sometimes needed in patients with SMA 2 and 3, infants with SMA 1 almost always struggle postoperatively 17,20 .…”

Section: Spinal Muscular Atrophymentioning

confidence: 99%

“…Even though opioids may further decrease respiratory drive, inadequate analgesia can result in splinting that limits chest wall excursion and re‐recruitment of atelectatic lung 17 . Although prolonged respiratory support after general anesthesia is sometimes needed in patients with SMA 2 and 3, infants with SMA 1 almost always struggle postoperatively 17,20 . Therefore, regional anesthesia in this patient population is appealing for many reasons.…”

Section: Spinal Muscular Atrophymentioning

confidence: 99%

“…SMA 0 is luckily very rare since it is the most severe in presentation and is typically discovered prenatally with death occurring almost immediately after birth. SMA 4, on the other hand, is often diagnosed in patients who live relatively normal lives, but exhibit slow deterioration in strength and progressive weakness in adulthood 13,17,18 . Recently, new promising biologic therapies, nusinersen and onasemnogene abeparvovec, have been shown to prolong the functional life of SMA patients by slowing disease progression 19 …”

Section: Spinal Muscular Atrophymentioning

confidence: 99%

See 3 more Smart Citations

Regional anesthesia in pediatric patients with preexisting neurological disease

Cung

Ritz

Masaracchia

2021

Pediatric Anesthesia

View full text Add to dashboard Cite

Preexisting neurological disease in pediatric patients presents unique challenges to the anesthesiologist. In‐depth knowledge of the disease processes and awareness of sequalae that uniquely influence the risks and benefits of anesthetics are needed to make informed decisions. Because these vulnerable populations are often susceptible to perioperative airway or cardiopulmonary complications, the use of regional anesthesia can be advantageous. However, these clinical conditions already involve compromised neural tissue and, as such, create additional concern that regional anesthesia may result in new or worsened deficits. The following discussion is not intended to be a full review of each disease process, but rather provides a concise, yet thorough, discussion of the available literature on regional anesthesia in the more common, but still rare, pediatric neurological disorders. We aim to provide a framework for pediatric anesthesiologists to reengage in a healthy discussion about the risks and benefits of utilizing regional anesthesia in this vulnerable population.

show abstract

“…Muscle atrophy, poor tone, and weakness are hallmarks of the disease. Ultimately, patients are unable to effectively clear secretions and respiratory insufficiency ensues 17 …”

Section: Spinal Muscular Atrophymentioning

confidence: 99%

Section: Spinal Muscular Atrophymentioning

confidence: 99%

Section: Spinal Muscular Atrophymentioning

confidence: 99%

Section: Spinal Muscular Atrophymentioning

confidence: 99%

See 2 more Smart Citations

Regional anesthesia in pediatric patients with preexisting neurological disease

Cung

Ritz

Masaracchia

2021

Pediatric Anesthesia

View full text Add to dashboard Cite

show abstract

“…The use of ultrasound during regional anesthesia can reduce the amount of local anesthetic and the incidence of hematomaif a blood vessel is injured (35). Therefore, regional anesthesia can be used, even in patients with disorders of the peripheral nervous system (18,26,36).…”

Section: Regional Anesthesiamentioning

confidence: 99%

Anesthesia and rare neuromuscular diseases

Radeka

Stojanović

Vasilijic

et al. 2023

Front. Anesthesiol.

View full text Add to dashboard Cite

Neuromuscular diseases, although rare in the general population, can be present in people who need to undergo surgery and anesthesia. Fortunately, the possibility of early diagnosis, new therapeutic approaches and the application of a multidisciplinary approach have significantly extended the life expectancy of such patients. The presence of such a disorder represents a challenge in anesthesiology practice, both during the preparation for surgery itself, the operative procedure and postoperative recovery in intensive care units. A basic understanding of the main disorders of the disease and their potential interactions with the anesthetic itself and the necessary agents in anesthesiology is necessary in order to reduce the risk of perioperative morbidity and mortality, with the aim of reducing the possibility of complications. Rare muscle diseases are very difficult to classify in a standard way because of the variability of their etiology and pathology. This work focuses on a number of muscle diseases such as Dubowitz syndrome, rhabdomyosarcoma in children, spinal muscular atrophy, Kennedy's disease, Congenital muscular dystrophy of the Ullrich type (UCMD), Sotos syndrome, Polymyositis and Setleis syndrome, Nemaline rod myopathy, Pompe disease, Emery-Dreifuss muscular dystrophy (EDMD). The medical literature on anesthetic techniques and perioperative complications was reviewed. Given that they can have a very unfavorable effect on the course of general anesthesia in particular and that these diseases can cause very serious, even life-threatening complications, an adequate anesthesiological approach is very important to reduce the possibility of the mentioned complications. A multidisciplinary approach is imperative for such patients before and after surgery, whether it is performed under analgosedation, some type of regional or general anesthesia. The operative procedure itself must be performed in institutions that are adequately equipped to treat such patients and by personnel who have experience in treating them.

show abstract

Neurologic Diseases

Scott¹,

Баранов²

2012

Anesthesia and Uncommon Diseases

View full text Add to dashboard Cite

Epidural anesthesia for the patient with type IV spinal muscular atrophy -A case report-

Cited by 5 publications

References 12 publications

Regional anesthesia in pediatric patients with preexisting neurological disease

Regional anesthesia in pediatric patients with preexisting neurological disease

Anesthesia and rare neuromuscular diseases

Neurologic Diseases

Contact Info

Product

Resources

About