2021
DOI: 10.1016/j.critrevonc.2021.103397
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Epigenetic modulation of the tumor microenvironment in head and neck cancer: Challenges and opportunities

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Cited by 10 publications
(5 citation statements)
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“…CS is a linear amino polysaccharide composed of monomeric units of N-acetyl-D-glucosamine and β-D-glucosamine linked by β-bonds [36,37]. Tis biopolymer has multiple attractive properties such as reactive functional groups for functionalization and crosslinking [38], solubility in acidic aqueous media, biodegradability, nonoxidation, biocompatibility, muco-adhesivity, and FDA approval for use in dietary products and wound dressings [39,40].…”
Section: Cs and Its Derivatives: Natural And Biological Propertiesmentioning
confidence: 99%
“…CS is a linear amino polysaccharide composed of monomeric units of N-acetyl-D-glucosamine and β-D-glucosamine linked by β-bonds [36,37]. Tis biopolymer has multiple attractive properties such as reactive functional groups for functionalization and crosslinking [38], solubility in acidic aqueous media, biodegradability, nonoxidation, biocompatibility, muco-adhesivity, and FDA approval for use in dietary products and wound dressings [39,40].…”
Section: Cs and Its Derivatives: Natural And Biological Propertiesmentioning
confidence: 99%
“…Tobacco use, Epstein-Barr virus (EBV), human papillomavirus (HPV), alcohol consumption and exposure to environmental carcinogenic factors are associated with DNA mutations and lead to dysplastic lesions in the head and neck area (3,4). Over the last decades, specific genes, which are responsible for hereditary types of HNC, have been identified (5).…”
Section: Epigenetic Editing and Tumor-dependent Immunosuppressive Sig...mentioning
confidence: 99%
“…Recent research has provided empirical evidence supporting the significant involvement of epigenetic mechanisms in HNSCC [13,14]. Epigenetics involves changes in heritable and reversible genetic characteristics without modifying the DNA sequence [15], including DNA methylation, histone modification, RNA editing, gene silencing and so forth [16].…”
Section: Introductionmentioning
confidence: 99%