Epigenética Do Exercício E Senescência

Cunha, Gabriel; Donato, Arthur Ney Alves; Parreira, Camila de Oliveira; Peres, Pedro Henrique Matias; Guerra, Christine Brasil; Tibana, Ramires Alsamir; Prestes, Jonato

doi:10.5935/2236-5117.2016v53a03

RBM

2016

DOI: 10.5935/2236-5117.2016v53a03

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Epigenética Do Exercício E Senescência

Gabriel Cunha¹,

Arthur Ney Alves Donato²,

Camila de Oliveira Parreira³

et al.

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Influence of genetics and epigenetics on the process of muscle hypertrophy: a systematic review

Fajardo Colorado,

Correa Jaramillo,

González Arango

2023

Mov Sport Sci/Sci Mot

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Muscle hypertrophy is the increase in the size of the transverse diameter of muscle fibers. Although the mechanisms and signaling pathways that regulate hypertrophy are known, it is still unclear how much genetics and epigenetics contribute to this process; whether both mechanisms participate jointly, or whether there is a more significant influence of one event than the other. Therefore, this study aimed to extensively review the literature and determine the role of genes and epigenetic mechanisms in regulating muscle hypertrophy associated with physical activity and sport. For this purpose, the Scopus and ScienceDirect databases were reviewed, and the PubMed and Google Scholar search engines were used, where 25 articles met the inclusion criteria. Results demonstrated that there are several regulatory genes of muscle hypertrophy, such as MSTN, PGC-1 α, STARS, and JunB, among others, as well as genetic polymorphisms and vital participation of DNA methylation, which together would control signaling pathways and gene networks necessary for the development of this process.

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Influence of genetics and epigenetics on the process of muscle hypertrophy: a systematic review

Fajardo Colorado,

Correa Jaramillo,

González Arango

2023

Mov Sport Sci/Sci Mot

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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Epigenética Do Exercício E Senescência

Cited by 1 publication

References 0 publications

Influence of genetics and epigenetics on the process of muscle hypertrophy: a systematic review

Influence of genetics and epigenetics on the process of muscle hypertrophy: a systematic review

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