Epigenomics of neurological disorders

Khorkova, Olga; Hsiao, Jane; Wahlestedt, Claes

doi:10.1016/b978-0-12-813955-4.00003-9

Cited by 1 publication

(1 citation statement)

References 169 publications

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“…After that, these authors investigated the molecular mechanism related to lncRNA HOX transcript antisense RNA (HOTAIR) modulation. Long non-coding RNAs (lncRNA) are usually related to a group of RNAs with more than 200 nucleotides and are not involved in protein generation, despite being involved in different regulatory processes, such as modulation of gene expression [125]. HOTAIR, which is over-expressed in different types of cancers, is a lncRNA that plays a role in carcinogenesis and cancer progression by promoting cancer cell viability, growth, and metastasis [126].…”

Section: Anthocyanins and Anthocyanidinsmentioning

confidence: 99%

Bioactive Compounds and Metabolites from Grapes and Red Wine in Breast Cancer Chemoprevention and Therapy

et al. 2020

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Phytochemicals and their metabolites are not considered essential nutrients in humans, although an increasing number of well-conducted studies are linking their higher intake with a lower incidence of non-communicable diseases, including cancer. This review summarizes the current findings concerning the molecular mechanisms of bioactive compounds from grapes and red wine and their metabolites on breast cancer—the most commonly occurring cancer in women—chemoprevention and treatment. Flavonoid compounds like flavonols, monomeric catechins, proanthocyanidins, anthocyanins, anthocyanidins and non-flavonoid phenolic compounds, such as resveratrol, as well as their metabolites, are discussed with respect to structure and metabolism/bioavailability. In addition, a broad discussion regarding in vitro, in vivo and clinical trials about the chemoprevention and therapy using these molecules is presented.

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Section: Anthocyanins and Anthocyanidinsmentioning

confidence: 99%